- Recombinant Proteins
- CD Antigens
- T Cell CD Proteins Macrophage CD Proteins Dendritic Cell CD Proteins
- CD8a
CD8a
CD8a is the alpha chain of the CD8 co-receptor, expressed as alpha-alpha homodimers or alpha-beta heterodimers on cytotoxic T lymphocytes, NK cells, and thymocytes. Each chain carries one extracellular immunoglobulin-like domain that docks onto the α3 domain of MHC class I molecules, stabilizing TCR recognition and allowing Lck, associated with the CD8 cytoplasmic tail, to phosphorylate the TCR complex. In the thymus, CD8 expression marks the cytotoxic lineage during positive selection. Anti-CD8a antibodies are indispensable tools for identifying cytotoxic T cells in immunophenotyping and tissue staining, and CD8a is used to track antitumor CD8+ T cell responses in cancer immunotherapy monitoring.
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CD8a Recombinant Proteins (15)
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- 1
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 1
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
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