1. JAK/STAT Signaling Protein Tyrosine Kinase/RTK GPCR/G Protein
  2. EGFR GPR35
  3. Tyrphostin 25

Tyrphostin 25  (Synonyms: AG82; Tyrphostin A 25; Tyrphostin AG 82; RG-50875)

Cat. No.: HY-101958
Handling Instructions

Tyrphostin 25 (AG82) is a specific inhibitor of the EGFR tyrosine kinase. Tyrphostin 25 is also a GPR35 agonist with an IC50 of 0.94 µM and an EC50 of 5.3 µM.

For research use only. We do not sell to patients.

Tyrphostin 25 Chemical Structure

Tyrphostin 25 Chemical Structure

CAS No. : 118409-58-8

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Description

Tyrphostin 25 (AG82) is a specific inhibitor of the EGFR tyrosine kinase. Tyrphostin 25 is also a GPR35 agonist with an IC50 of 0.94 µM and an EC50 of 5.3 µM[1][2].

IC50 & Target

EGFR tyrosine kinase[1]
IC50: 0.94 µM (GPR35)[2]
EC50: 5.3 µM (GPR35)[2]

Molecular Weight

202.17

Formula

C10H6N2O3

CAS No.
SMILES

N#C/C(C#N)=C/C1=CC(O)=C(O)C(O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tyrphostin 25
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