Oxynitidine
Oxynitidine is an HBV inhibitor (ID50=30.8 µg/mL), which can effectively inhibit the DNA replication activity of HBV. Oxynitidine can be used in the study of viral infections.
For research use only. We do not sell to patients.
- CAS No.: 548-31-2
- Formula: C21H17NO5
- Molecular Weight:363.36
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
39 μM
Compound: 1
|
Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay
Growth inhibition of human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| A549 | GI50 |
39.38 μM
Compound: 6
|
Growth inhibition of human A549 cells after 72 hrs by MTT assay
Growth inhibition of human A549 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| CCRF-CEM | GI50 |
26.52 μM
Compound: 6
|
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
Growth inhibition of human CCRF-CEM cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| DU-145 | GI50 |
64 μM
Compound: 1
|
Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay
Growth inhibition of human DU145 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| DU-145 | GI50 |
64.23 μM
Compound: 6
|
Growth inhibition of human DU145 cells after 72 hrs by MTT assay
Growth inhibition of human DU145 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| HCT-116 | GI50 |
74 μM
Compound: 1
|
Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay
Growth inhibition of human HCT116 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
| HCT-116 | GI50 |
74.79 μM
Compound: 6
|
Growth inhibition of human HCT116 cells after 72 hrs by MTT assay
Growth inhibition of human HCT116 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| Huh-7 | GI50 |
>100 μM
Compound: 6
|
Growth inhibition of human HuH7 cells after 72 hrs by MTT assay
Growth inhibition of human HuH7 cells after 72 hrs by MTT assay
|
[PMID: 30336023] |
| MCF7 | GI50 |
31 μM
Compound: 1
|
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
Growth inhibition of human MCF7 cells incubated for 72 hrs by MTT assay
|
[PMID: 31176097] |
Chemical Information
-
CAS No. 548-31-2
-
Molecular Weight 363.36
-
Formula C21H17NO5
-
SMILES
O=C1C2=CC(OC)=C(C=C2C3=C(N1C)C4=CC5=C(OCO5)C=C4C=C3)OC
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)