1. Metabolic Enzyme/Protease
  2. RAR/RXR
  3. WYC-209

WYC-209 

Cat. No.: HY-124136
Handling Instructions

WYC-209 is a synthetic retinoid, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. The primary cellular target of WYC-209 is retinoic acid receptors (RARs).

For research use only. We do not sell to patients.

WYC-209 Chemical Structure

WYC-209 Chemical Structure

CAS No. : 2131803-90-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 495 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2250 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3350 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

WYC-209 is a synthetic retinoid, which inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with an IC50 of 0.19 μM. The primary cellular target of WYC-209 is retinoic acid receptors (RARs)[1].

IC50 & Target

Retinoic acid receptors[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (226.16 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7141 mL 13.5704 mL 27.1407 mL
5 mM 0.5428 mL 2.7141 mL 5.4281 mL
10 mM 0.2714 mL 1.3570 mL 2.7141 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.65 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.65 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

368.45

Formula

C₂₀H₂₀N₂O₃S

CAS No.

2131803-90-0

SMILES

O=C(C1=CN=C(C#CC2=CC=C3C(C(C)(C)CCS3=O)=C2)N=C1)OCC

Shipping

Room temperature in continental US; may vary elsewhere

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
WYC-209
Cat. No.:
HY-124136
Quantity:

WYC-209

Cat. No.: HY-124136