2. GPCR/G Protein Others Neuronal Signaling Apoptosis Metabolic Enzyme/Protease
  3. Adrenergic Receptor Reference Standards Apoptosis Caspase Bcl-2 Family HIF/HIF Prolyl-Hydroxylase
  4. Zenidolol (Standard)

Zenidolol (Standard)  (Synonyms: ICI-118551 (Standard))

Cat. No.: HY-100543R Purity: 95%
Handling Instructions Technical Support

Zenidolol (ICI-118551) (Standard) is the analytical standard of Zenidolol (HY-100543). This product is intended for research and analytical applications. Zenidolol is a selective β2-adrenergic receptor antagonist with Ki values of Zenidolol for β2, β1 and β3 adrenergic receptors of 0.7, 49.5 and 611 nM, respectively. Zenidolol exerts antitumor effects via inducing apoptosis, inhibiting tumor sphere formation, and downregulating the HIF pathway by blocking β2-AR on tumor cells. Zenidolol exhibits a unique pulmonary vessel-specific vasodilatory effect in mouse models. Zenidolol can be used as an intraocular pressure-lowering agent in ophthalmic disease research.

For research use only. We do not sell to patients.

Zenidolol (Standard)

Zenidolol (Standard) Chemical Structure

CAS No. : 72795-26-7

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5 mg Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
10 mg Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
25 mg Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
50 mg Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
100 mg Get quote 4 - 6 Weeks 3 - 5 Weeks 5 - 7 Weeks 4 - 6 weeks
200 mg   Get quote  
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Information

Zenidolol (ICI-118551) (Standard) is the analytical standard of Zenidolol (HY-100543). This product is intended for research and analytical applications. Zenidolol is a selective β2-adrenergic receptor antagonist with Ki values of Zenidolol for β2, β1 and β3 adrenergic receptors of 0.7, 49.5 and 611 nM, respectively. Zenidolol exerts antitumor effects via inducing apoptosis, inhibiting tumor sphere formation, and downregulating the HIF pathway by blocking β2-AR on tumor cells. Zenidolol exhibits a unique pulmonary vessel-specific vasodilatory effect in mouse models. Zenidolol can be used as an intraocular pressure-lowering agent in ophthalmic disease research.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

277.40

Formula

C17H27NO2
CAS No.
SMILES

C[C@@H](NC(C)C)[C@@H](O)COC1=CC=C(C)C2=C1CCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Zenidolol (Standard) Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zenidolol (Standard)72795-26-7ICI-118551 (Standard)Adrenergic ReceptorReference StandardsApoptosisCaspaseBcl-2 FamilyHIF/HIF Prolyl-HydroxylaseBeta ReceptorHypoxia-inducible factorsHIFsHIF-PHocular hypotensive agenteadenylatecyclasecAMPselectiveInhibitorinhibitorinhibit

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