1-Methyladenosine

Cat. No.: HY-113081 Purity: 98.36%: FAQs
Data Sheet SDS COA Handling Instructions

1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.

For research use only. We do not sell to patients.

1-Methyladenosine Chemical Structure

CAS No. : 15763-06-1

Size	Price	Stock	Quantity
Solution
10 mM * 1 mL in DMSO	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL ready for reconstitution	USD 66	In-stock	Estimated Time of Arrival: December 31
Solid
50 mg	USD 60	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 2 publication(s) in Google Scholar

2 Publications Citing Use of MCE 1-Methyladenosine

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Human Endogenous Metabolite

Molecular Weight

281.27

Appearance

Solid

Formula

C₁₁H₁₅N₅O₄

CAS No.

15763-06-1

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN(C)C3=N)=C3N=C2)O1

Structure Classification

Alkaloids

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 150 mg/mL (533.30 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.5553 mL	17.7765 mL	35.5530 mL
5 mM	0.7111 mL	3.5553 mL	7.1106 mL
10 mM	0.3555 mL	1.7777 mL	3.5553 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: ≥ 2.08 mg/mL (7.40 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.08 mg/mL (7.40 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO 90% corn oil
Solubility: ≥ 2.08 mg/mL (7.40 mM); Clear solution

*All of the co-solvents are available by MCE.

Purity & Documentation

Purity: 98.36%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (252 KB) HNMR (219 KB) LCMS (255 KB)

Handling Instructions (2659 KB)

References

[1]. Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64. [Content Brief]