2-Acetoxyacorenone
2-Acetoxyacorenone (compound 8) is a sesquiterpenoid, which can be isolated from the rhizome of Acorus tatarinowii. 2-Acetoxyacorenone has potent AChE and β-BACE1 inhibitory activity and can be used in the study of Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 185154-95-4
- Formula: C17H26O3
- Molecular Weight:278.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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AChE |
BACE1 |
Chemical Information
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CAS No. 185154-95-4
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Molecular Weight 278.39
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Formula C17H26O3
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SMILES
CC([C@H]1[C@@]2(CC(C(C)=CC2)=O)[C@H](C[C@H]1OC(C)=O)C)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)