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Cat. No.: HY-103064

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2-Methylthio-AMP sodium

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

2-Methylthio-AMP sodium is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP sodium is an inhibitor of ADP-dependent platelet aggregation.

For research use only. We do not sell to patients.

CAS No.: 81921-45-1
Formula: C₁₁H₁₄N₅Na₂O₇PS
Molecular Weight:437.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

2-Methylthio-AMP sodium Chemical Structure

CAS No.: 81921-45-1

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Description

2-Methylthio-AMP sodium is a selective and direct P2Y₁₂ antagonist. 2-Methylthio-AMP sodium is an inhibitor of ADP-dependent platelet aggregation^[1]^[2]^[3].

All P2Y Receptor Isoforms :

Chemical Information

CAS No. 81921-45-1
Molecular Weight 437.28
Formula C₁₁H₁₄N₅Na₂O₇PS
SMILES

O[C@H]1[C@@H](O)[C@H](N2C3=C(N=C2)C(N)=NC(SC)=N3)O[C@@H]1COP(O[Na])(O[Na])=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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bioRxiv

2023 Oct 9.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. John H Cleator, et al. Racial differences in resistance to P2Y12 receptor antagonists in type 2 diabetic subjects. J Pharmacol Exp Ther. 2014 Oct;351(1):33-43. [Content Brief]

[2]. Bernhard H Rauch, et al. Regulation of functionally active P2Y12 ADP receptors by thrombin in human smooth muscle cells and the presence of P2Y12 in carotid artery lesions. Arterioscler Thromb Vasc Biol. 2010 Dec;30(12):2434-42. [Content Brief]

[3]. A Malinin, et al. Validation of a VerifyNow-P2Y12 cartridge for monitoring platelet inhibition with clopidogrel. Methods Find Exp Clin Pharmacol. 2006 Jun;28(5):315-22. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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2-Methylthio-AMP sodium

1 Cited Publications

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2-Methylthio-AMP sodium

Publications Citing Use of MedChemExpress (MCE) 2-Methylthio-AMP sodium

All P2Y Receptor Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

2-Methylthio-AMP sodium Related Classifications

HY-103064 Related Classifications