1. Apoptosis
  2. Bcl-2 Family
  3. Bak BH3

Bak BH3 

Cat. No.: HY-P0300
Handling Instructions

Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Bak BH3 Chemical Structure

Bak BH3 Chemical Structure

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1 mg USD 132 Ask For Quote & Lead Time
5 mg USD 396 Ask For Quote & Lead Time
10 mg USD 660 Ask For Quote & Lead Time

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Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.

IC50 & Target[1]



In Vitro

Bak BH3 peptide antagonize the protective effects of microinjected Bcl-xL in α-Fas-treated HeLa cells, whereas a mutant Bak BH3 peptide that no longer binds Bcl-xL is inactive[1].

Molecular Weight






Sequence Shortening



Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

Cell Assay

Cells are plated in complete DMEM in 96-well tissue culture plates at 4×103/well. After 24 h, cells are washed with PBS and treated with peptides (50 μM) in SF-DMEM. Cell viability is determined by staining unfixed cells with calcein AM/ethidium homodimer, followed by microscopic analysis of cell staining and cellular morphology on a Nikon Diaphot 300 inverted microscope equipped with a fluorescence module.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2


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