Bak BH3
Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells.
For research use only. We do not sell to patients.
- CAS No.: 300349-67-1
- Formula: C72H125N25O24
- Molecular Weight:1724.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Bcl-xL |
Chemical Information
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CAS No. 300349-67-1
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Molecular Weight 1724.90
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Formula C72H125N25O24
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Sequence
Gly-Gln-Val-Gly-Arg-Gln-Leu-Ala-Ile-Ile-Gly-Asp-Asp-Ile-Asn-Arg
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Sequence Shortening
GQVGRQLAIIGDDINR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
Cells are plated in complete DMEM in 96-well tissue culture plates at 4×103/well. After 24 h, cells are washed with PBS and treated with peptides (50 μM) in SF-DMEM. Cell viability is determined by staining unfixed cells with calcein AM/ethidium homodimer, followed by microscopic analysis of cell staining and cellular morphology on a Nikon Diaphot 300 inverted microscope equipped with a fluorescence module.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)