1. Epigenetics
  2. Histone Acetyltransferase
  3. CTPB

CTPB 

Cat. No.: HY-124960 Purity: >99.0%
Handling Instructions

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme.

For research use only. We do not sell to patients.

CTPB Chemical Structure

CTPB Chemical Structure

CAS No. : 586976-24-1

Size Price Stock Quantity
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 750 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

IC50 & Target[1]

p300

 

In Vitro

CTPB is a synthetic HAT activator, which promotes the transcription by increasing the H3 and H4 acetylation in nucleosome[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

554.13

Formula

C₃₁H₄₃ClF₃NO₂

CAS No.

586976-24-1

SMILES

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (112.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8046 mL 9.0232 mL 18.0463 mL
5 mM 0.3609 mL 1.8046 mL 3.6093 mL
10 mM 0.1805 mL 0.9023 mL 1.8046 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (3.75 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.75 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.75 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >99.0%

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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CTPBHistone AcetyltransferaseHATsHATInhibitorinhibitorinhibit

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Product Name:
CTPB
Cat. No.:
HY-124960
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