2. Epigenetics
  3. Histone Acetyltransferase
  4. CTPB

CTPB 

Cat. No.: HY-124960 Purity: ≥98.0%
COA Handling Instructions

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme.

For research use only. We do not sell to patients.

CTPB Chemical Structure

CTPB Chemical Structure

CAS No. : 586976-24-1

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 366 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 366 In-stock
Estimated Time of Arrival: December 31
Solid
5 mg USD 300 In-stock
Estimated Time of Arrival: December 31
10 mg USD 480 In-stock
Estimated Time of Arrival: December 31
25 mg USD 960 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1540 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2460 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products

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Description

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

IC50 & Target[1]

CBP/p300

 

In Vitro

CTPB is a synthetic HAT activator, which promotes the transcription by increasing the H3 and H4 acetylation in nucleosome[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

554.13

Appearance

Solid

Formula

C31H43ClF3NO2
CAS No.
SMILES

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (112.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8046 mL 9.0232 mL 18.0463 mL
5 mM 0.3609 mL 1.8046 mL 3.6093 mL
10 mM 0.1805 mL 0.9023 mL 1.8046 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (3.75 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (3.75 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (3.75 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥99.0%

COA (244 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

CTPB586976-24-1Histone AcetyltransferaseHATsHATInhibitorinhibitorinhibit

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