1. GPCR/G Protein
  2. LPL Receptor

LPA2 antagonist 1 

Cat. No.: HY-18075 Purity: 98.85%
Handling Instructions

LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM.

For research use only. We do not sell to patients.

LPA2 antagonist 1 Chemical Structure

LPA2 antagonist 1 Chemical Structure

CAS No. : 1017606-66-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 462 In-stock
Estimated Time of Arrival: December 31
5 mg USD 420 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1800 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2520 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM.

IC50 & Target

IC50: 17 nM (LPA2)[1]

In Vitro

LPA2 antagonist 1 inhibits the phosphorylation of Erk induced by LPA in a concentration dependent manner. LPA2 antagonist 1 inhibits HCT-116 colon cancer cell proliferation caused by LPA in a doses dependent manner[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9982 mL 9.9908 mL 19.9816 mL
5 mM 0.3996 mL 1.9982 mL 3.9963 mL
10 mM 0.1998 mL 0.9991 mL 1.9982 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

500.46

Formula

C₂₀H₂₃Cl₂N₅O₂S₂

CAS No.

1017606-66-4

SMILES

ClC1=C(Cl)C=C(S(=O)(N2CCN(C[[email protected]@H](NC3=NC=NC4=C3SC=C4C)C)CC2)=O)C=C1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
LPA2 antagonist 1
Cat. No.:
HY-18075
Quantity:

LPA2 antagonist 1

Cat. No.: HY-18075