1. MAPK/ERK Pathway
    Autophagy
  2. p38 MAPK
    Autophagy
  3. MAPK13-IN-1

MAPK13-IN-1 

Cat. No.: HY-18850 Purity: 98.47%
Handling Instructions

MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.

For research use only. We do not sell to patients.

MAPK13-IN-1 Chemical Structure

MAPK13-IN-1 Chemical Structure

CAS No. : 229002-10-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 550 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2650 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.

IC50 & Target

MAPK13 (p38δ)

620 nM (IC50)

Molecular Weight

365.43

Formula

C₂₀H₂₃N₅O₂

CAS No.

229002-10-2

SMILES

O=C(NC1=CC=C(OC2=CC=NC=C2)C=C1)NC3=CC(C(C)(C)C)=NN3C

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (684.13 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7365 mL 13.6825 mL 27.3650 mL
5 mM 0.5473 mL 2.7365 mL 5.4730 mL
10 mM 0.2737 mL 1.3683 mL 2.7365 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.69 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
MAPK13-IN-1
Cat. No.:
HY-18850
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