1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Metipranolol hydrochloride

Metipranolol hydrochloride 

Cat. No.: HY-16316 Purity: 99.94%
Handling Instructions

Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent.

For research use only. We do not sell to patients.

Metipranolol hydrochloride Chemical Structure

Metipranolol hydrochloride Chemical Structure

CAS No. : 36592-77-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 240 In-stock
Estimated Time of Arrival: December 31
25 mg USD 480 In-stock
Estimated Time of Arrival: December 31
50 mg USD 850 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent.

IC50 & Target

β adrenergic receptor [1].

In Vitro

Metipranolol is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma[1].

Molecular Weight

345.86

Formula

C₁₇H₂₈ClNO₄

CAS No.

36592-77-5

SMILES

CC1=C(OC(C)=O)C(C)=C(C)C(OCC(O)CNC(C)C)=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (289.13 mM)

DMSO : 100 mg/mL (289.13 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8913 mL 14.4567 mL 28.9134 mL
5 mM 0.5783 mL 2.8913 mL 5.7827 mL
10 mM 0.2891 mL 1.4457 mL 2.8913 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.23 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.23 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.23 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product name:
Metipranolol hydrochloride
Cat. No.:
HY-16316
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