1. Others
  2. Aromatase
  3. Org30958


Cat. No.: HY-U00176
Handling Instructions

Org30958 is a potent aromatase inhibitor in vivo.

For research use only. We do not sell to patients.

Org30958 Chemical Structure

Org30958 Chemical Structure

CAS No. : 99957-90-1

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Org30958 is a potent aromatase inhibitor in vivo.

IC50 & Target


In Vivo

Besides inhibition of cornification of vaginal epithelium Org30958 (ORG 30958) decreases ovarian aromatase and plasma E2 levels in DHEAS-treated hypophysectomized rats. Plasma estradiol levels are also lowered by Org30958 in dogs which are treated with pregnant mare serum gonadotrophin in order to induce pro-estrus. Org30958 displays much less than 1/400th of the androgenic activity of testosterone propionate in immature castrated rats and appears to be devoid of estrogenic and anti-estrogenic activity in ovariectomized mature rats. A twice daily dose of 1.5 mg Org30958/kg postpones ovulation in mature female rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





Room temperature in continental US; may vary elsewhere.


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