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  3. Org30958

Org30958 

Cat. No.: HY-U00176
Handling Instructions

Org30958 is a potent aromatase inhibitor in vivo.

For research use only. We do not sell to patients.

Org30958 Chemical Structure

Org30958 Chemical Structure

CAS No. : 99957-90-1

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Description

Org30958 is a potent aromatase inhibitor in vivo.

IC50 & Target

Aromatase[1]

In Vivo

Besides inhibition of cornification of vaginal epithelium Org30958 (ORG 30958) decreases ovarian aromatase and plasma E2 levels in DHEAS-treated hypophysectomized rats. Plasma estradiol levels are also lowered by Org30958 in dogs which are treated with pregnant mare serum gonadotrophin in order to induce pro-estrus. Org30958 displays much less than 1/400th of the androgenic activity of testosterone propionate in immature castrated rats and appears to be devoid of estrogenic and anti-estrogenic activity in ovariectomized mature rats. A twice daily dose of 1.5 mg Org30958/kg postpones ovulation in mature female rats[1].

Molecular Weight

378.59

Formula

C₂₁H₃₀O₂S₂

CAS No.

99957-90-1

SMILES

CCSSC[[email protected]@]12[[email protected]]3([H])[[email protected]](CCC1=CC(CC2)=O)([H])[[email protected]@]4([H])[[email protected]@](C)(C(CC4)=O)CC3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Org30958Org 30958Org-30958AromataseInhibitorinhibitorinhibit

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