1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-103095A
    Enmetazobactam iodide
    Enmetazobactam (iodide) (AAI101 (iodide)) is an extended-spectrum β-lactamase inhibitor, against many resistant Gram-negative pathogens.
    Enmetazobactam iodide
  • HY-148568
    TMV-IN-2
    TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor.
    TMV-IN-2
  • HY-B1894
    Cefetamet pivoxyl
    Cefetamet pivoxyl (Ro 15-8075 free base) is an orally active cephalosporin Antibiotic and a prodrug of Cefetamet (HY-A0111). After ingestion, Cefetamet pivoxyl is hydrolyzed by gastrointestinal esterases to form Cefetamet. Cefetamet pivoxyl is primarily active against aerobic Gram-negative bacteria (such as Enterobacteriaceae, *Neisseria*, *Haemophilus*) and some Gram-positive bacteria (such as non-enterococcal streptococci). Cefetamet pivoxyl exhibits potent in vivo antibacterial activity against strains of Gram-positive bacteria (S. pyogenes) and Gram-negative bacteria (E. coli, K. pneumoniae, S. marcescens, P. vulgaris, P. mirabilis, H. influenzae).
    Cefetamet pivoxyl
  • HY-148209
    Balhimycin
    Inhibitor
    Balhimycin is a glycopeptide antibiotic, found from the fermentation broth of a Amycolatopsis sp. Balhimycin shows anti-bacterial activity against staphylococci and anaerobes.
    Balhimycin
  • HY-A0110AR
    Cefotiam hexetil hydrochloride (Standard)
    Inhibitor
    Cefotiam hexetil (hydrochloride) (Standard) is the analytical standard of Cefotiam hexetil (hydrochloride). This product is intended for research and analytical applications. Cefotiam hexetil hydrochloride (CTM-HE) is an oral third-generation cephalosporin, which is a proagent of cefotiam, but has no anti-bacterial property. Cefotiam is an antibiotic[1].
    Cefotiam hexetil hydrochloride (Standard)
  • HY-139645
    MtDTBS-IN-1
    Inhibitor
    MtDTBS-IN-1 is a particularly potent binder (KD = 57 nM) and inhibitor (Ki = 5 μM) of MtDTBS.
    MtDTBS-IN-1
  • HY-117492
    Aconiazide
    Inhibitor
    Aconiazide (Isonicophen) is a orally active hydrazone derivative of isoniazid, and can be used for study of tuberculosis.
    Aconiazide
  • HY-139766
    Antibacterial agent 49
    Inhibitor
    Antibacterial agent 49 (example 12) is a antibacterial agent (extracted from patent WO2013030735A1).
    Antibacterial agent 49
  • HY-121329
    Carumonam
    Inhibitor
    Carumonam (AMA-1080; Ro 17-2301) is a sulfonated monocyclic β-Lactam Antibiotic, targeting to penicillin-binding protein (PBP). Carumonam exerts highly activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while it weakly and even inactively inhibits Streptococcus pneumoniae and Staphylococcus aureus. Carumonam is resistant to beta-lactamase-mediated hydrolysis.
    Carumonam
  • HY-139757
    Antibacterial agent 40
    Antibacterial agent 40 is an antibacterial agent (extracted from patent WO2015159265A1, compound C) .
    Antibacterial agent 40
  • HY-119686
    Miloxacin
    Inhibitor
    Miloxacin is an orally active bacteriostatic agent targeting Gram-negative bacteria, exhibiting antibacterial properties similar to Oxolinic acid (HY-B1002) and Nalidixic acid (HY-B0398).
    Miloxacin
  • HY-W777154
    Zoledronic acid-15N2,13C2
    Zoledronic acid-15N2,13C2 (CGP 42446-15N2,13C2) is the 13C- and 15N-labeled Zoledronic Acid (HY-13777). Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects.
    Zoledronic acid-<sup>15</sup>N<sub>2</sub>,<sup>13</sup>C<sub>2</sub>
  • HY-N18766
    Hibiscus sabdariffa extract
    Hibiscus sabdariffa extract contains a variety of active ingredients, including anthocyanins, flavonoids, vitamin C, and organic acids such as citric acid and malic acid. Hibiscus sabdariffa extract possesses antioxidant, anti-inflammatory, antibacterial, and antiviral properties.
    Hibiscus sabdariffa extract
  • HY-149998
    Antimycobacterial agent-5
    Inhibitor
    Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide targeting mycobacterial electron transport chain (ETC) airway CIII2CIV2 supercomplexes. The IC50 value of Antimycobacterial agent-5 against Mycobacterium smegmatisCIII2CIV2 is 441 nM.
    Antimycobacterial agent-5
  • HY-B0268AR
    Enoxacin hydrate (Standard)
    Inhibitor
    Enoxacin (hydrate) (Standard) is the analytical standard of Enoxacin (hydrate). This product is intended for research and analytical applications. Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 μg/ml) and topoisomerase IV (IC50=26.5 μg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing[4].
    Enoxacin hydrate (Standard)
  • HY-139618R
    Dup-721 (Standard)
    Inhibitor
    Celiprolol (hydrochloride) (Standard) is the analytical standard of Celiprolol (hydrochloride). This product is intended for research and analytical applications. Celiprolol (REV 5320) is a potent, cardioselective and orally active β1-andrenoceptor r antagonist with partial β2 agonist activity, with Ki values of 0.14-8.3 μM. Celiprolol has antihypertensive and antianginal activity, and can be used for the research of cardiovascular disease such as high blood pressure.
    Dup-721 (Standard)
  • HY-157987
    MBX3135
    MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics.
    MBX3135
  • HY-116282P
    Dextran sulfate, high sulfate (MW 5000)
    Inhibitor
    Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing.
    Dextran sulfate, high sulfate (MW 5000)
  • HY-106572A
    Cefbuperazone sodium
    Cefbuperazone sodium is an antibacterial agent that demonstrates significant activity against bacterial infections. Cefbuperazone sodium exhibits a linear pharmacokinetic profile, allowing for effective dosage determination in clinical settings. Cefbuperazone sodium reaches peak concentrations in human plasma following intravenous infusion, indicating its rapid absorption and distribution. Cefbuperazone sodium is primarily excreted unchanged in urine, highlighting its efficiency in renal elimination.
    Cefbuperazone sodium
  • HY-147546
    Antibacterial agent 107
    Inhibitor
    Antibacterial agent 107 (compound 14) is a potent antibacterial agent. Antibacterial agent 107 shows potent antibacterial activity against Gram-positive bacteria, with a MIC of 1.56 μg/mL (MRSA). Antibacterial agent 107 exhibits low hemolytic activity, high membrane selectivity, and rapid bactericidal activity. Antibacterial agent 107 shows effective in vivo efficacy in the murine model of bacterial keratitis caused by Staphylococcus aureus ATCC29213.
    Antibacterial agent 107
Cat. No. Product Name / Synonyms Application Reactivity