Epigenetic Reader Domain
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Epigenetic Reader Domain Inhibitors
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Epigenetic Reader Domain Degraders
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Epigenetic Reader Domain Controls
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Epigenetic Reader Domain Substrate
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Epigenetic Reader Domain Ligands
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Epigenetic Reader Domain Related Products (447)
Related Products (447)
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CREB-IN-1 TFA
0 ImagesCat. No.: HY-144318CAS No.: 2912285-84-6CREB-IN-1 TFA is a potent, orally active CREB inhibitor (IC50=0.18 µM). CREB-IN-1 TFA inhibits breast cancer cell growth.
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(1s,4s)-Menin-MLL inhibitor-23
0 ImagesCat. No.: HY-148367A(1s,4s)-Menin-MLL inhibitor-23 is the enantiomer of Menin-MLL inhibitor-23 (HY-148367). Menin-MLL inhibitor-23 (Example 99A) is a menin-MLL interaction inhibitor.
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BET-IN-23
0 ImagesCat. No.: HY-163160CAS No.: 2953287-57-3Bet-in-23 (Compound 23) is a BD2-selective BET inhibitor with an IC50 of 2.9 nM. BET-IN-23 has anticancer activity and can significantly inhibit the proliferation of acute myeloid leukemia (AML) cell lines by inducing G0/G1 arrest and apoptosis in vitro.
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CREBBP-IN-1
0 ImagesCat. No.: HY-114971CAS No.: 1801324-41-3CREBBP-IN-1 (Compound 10) exhibits good affinity with CREBBP bromodomain with Kd of 0.77 μM.
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CZL-046
0 ImagesCat. No.: HY-168148SCAS No.: 3032444-02-0CZL-046 (compund 29) is an oral p300 bromodomain inhibitor.
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Anacardic Acid (Standard)
0 ImagesSynonyms: Hydroginkgolic acid (Standard); Ginkgolic Acid C15:0 (Standard)Anacardic Acid (Standard) is the analytical standard of Anacardic Acid. This product is intended for research and analytical applications. Anacardic Acid, extracted from cashew nut shell liquid, is a histone acetyltransferase inhibitor, inhibits HAT activity of p300 and PCAF, with IC50s of ～8.5 μM and ～5 μM, respectively.
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JP-2-196
0 ImagesCat. No.: HY-W854844CAS No.: 2913587-30-9JP-2-196 is a molecular glue that covalently targets the RING family E3 ligase RNF126. JP-2-196 also binds to RNF40, MID2, RNF219, RNF14, and LRSAM1. JP-2-196 induces the formation of ternary complexes between RNF126 and target proteins (e.g., BRD4, AR-V7), thereby promoting their ubiquitination and proteasomal degradation. JP-2-196 has potential for cancer research (such as prostate cancer and leukemia).
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CREBBP-IN-9
0 ImagesCat. No.: HY-116237CAS No.: 1219576-50-7CREBBP-IN-9 (Compound 9) is an inhibitor for CREBBP with an Kd of 29 μM.
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GSK232
0 ImagesCat. No.: HY-145347CAS No.: 2702984-69-6GSK232 is a highly selective, cellularly penetrant CECR2 inhibitor with excellent physicochemical properties.
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BRD4-IN-7
0 ImagesCat. No.: HY-160671CAS No.: 1446232-98-9BRD4-IN-7 (compound 120) is a BRD4 inhibitor(extracted from patent CN107721975A).
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MI-1
0 ImagesCat. No.: HY-111937CAS No.: 433311-07-0MI-1 inhibits Menin-MLL interaction with an IC50 of 1.9 μM.
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P53/BET TCIP-1
0 ImagesCat. No.: HY-184518P53/BET TCIP-1 (Compound 47) is a dual-functional hybrid molecule that possesses both reactivation of p53 Y220C (EC50 ≤ 100 nM) and inhibition of BRD4/BET (EC50 ≤ 500 nM) dual activities. P53/BET TCIP-1 exhibits significant inhibitory proliferation activity in p53 Y220C mutant tumor cells. P53/BET TCIP-1 can be used to study p53 Y220C mutation-related cancers (such as ovarian cancer, pancreatic cancer, gastric cancer, etc.).
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Bromodomain IN-1
0 ImagesCat. No.: HY-116349CAS No.: 1914120-48-1Bromodomain IN-1 is a Bromodomain inhibitor extracted from patent WO2016069578A1, compound 4 .
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Y08060
0 ImagesCat. No.: HY-124585CAS No.: 2222565-19-5Y08060 is a selective BET inhibitor. Y08060 inhibits the viability of C4-2B and LNCaP cell lines with IC50 values of 3.23 and 4.41 μM. Y08060 can suppress colony formation as well as AR expression in prostate cancer cell line. Y08060 can be studied in prostate cancer research.
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Bromodomain inhibitor-13
0 ImagesCat. No.: HY-122573CAS No.: 1914047-59-8Bromodomain inhibitor-13 (Compound 1) is an analog of PFI-3 (HY-12409). Bromodomain inhibitor-13 is a bromodomain-containing protein (BCP) inhibitor. Bromodomain inhibitor-13 targets SMARCA2, SMARCA4, PB1(5), and second bromodomain of PB1 (PB1(2)) with KD values of 37, 53, 30, and 190 nM, respectively.
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Eleven-Nineteen-Leukemia Protein IN-2
0 ImagesCat. No.: HY-152470CAS No.: 2894121-78-7Eleven-Nineteen-Leukemia Protein IN-2 (compound 23) is an Eleven-Nineteen-Leukemia Protein (ENL) inhibitor with an IC50 value of 10.7 nM. Eleven-Nineteen-Leukemia Protein IN-2 can be used for the research of leukemia.
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CDC14A/B-IN-1
0 ImagesCat. No.: HY-161673CAS No.: 3048655-03-1CDC14A/B-IN-1 (Compound 15) is an orally available inhibitor of CDC14A/B phosphatases with Ki values ??of 57.4 nM (CDC14A) and 90.0 nM (CDC14B), respectively.
