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Cat. No.: HY-114971

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CREBBP-IN-1

CREBBP-IN-1 (Compound 10) exhibits good affinity with CREBBP bromodomain with K_d of 0.77 μM.

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CAS No.: 1801324-41-3
Formule: C₁₈H₁₇NO₅
Masse moléculaire:327.33

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CREBBP-IN-1 Chemical Structure

CAS No.: 1801324-41-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

CREBBP-IN-1 (Compound 10) exhibits good affinity with CREBBP bromodomain with K_d of 0.77 μM^[1].

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Chemical Information

CAS No. 1801324-41-3
Masse moléculaire 327.33
Formule C₁₈H₁₇NO₅
SMILES

O=C(C1=CC=CC(C(NC2=CC(C(C)=O)=CC=C2OCC)=O)=C1)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xu M, et al., Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics. J Med Chem. 2016 Feb 25;59(4):1340-9. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureté et documentation
Références

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CREBBP-IN-1

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