1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. FXR
  4. FXR Inhibitor

FXR Inhibitor

FXR Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-114392
    Gly-β-MCA
    Inhibitor 98.11%
    Gly-β-MCA, a bile acid, is a potent, sable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor that may be a candidate for the treatment of metabolic disorders.
  • HY-13995A
    Sevelamer hydrochloride
    Inhibitor ≥98.0%
    Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin.
  • HY-13995
    Sevelamer
    Inhibitor
    Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
  • HY-151959
    FXR agonist 4
    Inhibitor
    FXR agonist 4 (compound 10a) is an agonist of farnesoid X receptor (FXR) with an EC50 value of 1.05 μM. FXR agonist 4 effectively improves hyperlipidemia, hepatic steatosis, insulin resistance and hepatic inflammation in DIO mice. FXR agonist 4 can be used for the research of non-alcoholic fatty liver disease (NAFLD).