GlyT
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GlyT Related Products (30)
Related Products (30)
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Sarcosine (Standard)
0 ImagesSynonyms: N-Methylglycine (Standard); Sarcosin (Standard)Sarcosine (Standard) is the analytical standard of Sarcosine. This product is intended for research and analytical applications. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia.
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ALX-1393 TFA
0 ImagesCat. No.: HY-111029APurity: 99.83%ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model.
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N-Arachidonylglycine-d8
0 ImagesSynonyms: NA-Gly-d8N-Arachidonylglycine-d8 is a deuterated labeled N-Arachidonylglycine. N-Arachidonylglycine (NA-Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44.5 nM). Unlike AEA, N-Arachidonylglycine has no activity at either CB1 or CB2 receptors. N-Arachidonylglycine inhibits GLYT2 (IC50 = 5.1 μM). N-Arachidonylglycine also is an effective activator of endometrial cell migration.
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MPDC
0 ImagesCat. No.: HY-101334CAS No.: 159262-32-5MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes.
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Bitopertin (R enantiomer)
0 ImagesCat. No.: HY-10809ACAS No.: 845614-12-2Synonyms: RG1678 (R enantiomer); RO4917838 (R enantiomer)Bitopertin R enantiomer (RG1678 R enantiomer; RO4917838 R enantiomer) is the R-enantiomer of Bitopertin. Bitopertin is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM.
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LY2365109
0 ImagesCat. No.: HY-100416CAS No.: 868265-28-5LY2365109 is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
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Org 25543
0 ImagesCat. No.: HY-107527ACAS No.: 363628-88-0Org 25543 is a selective inhibitor of the glycine transporter 2, exhibiting analgesic properties in a rat model of chronic pain.
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(Rac)-Oleoylcarnitine
0 ImagesCat. No.: HY-113261ACAS No.: 13962-05-5(Rac)-Oleoylcarnitine is an endogenous acylcarnitine and a potential noncompetitive inhibitor of glycine transporter 2 (GLYT2) that can be used as a pain suppressant.
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Org-24598 lithium
0 ImagesCat. No.: HY-10713CAS No.: 722456-08-8Org-24598 lithium is an inhibitor of glycine transporter 1 GlyT-1 . Org-24598 lithium can inhibit the specific binding of [3H] CHIBIA-3007 to the rat brain membranes with a Ki value of 16.9 nM.
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DCCCyB
0 ImagesCat. No.: HY-14568CAS No.: 1236046-15-3
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Sarcosine-13C3
0 ImagesCat. No.: HY-W748519CAS No.: 2806125-84-6Synonyms: N-Methylglycine-13C3; Sarcosin-13C3Sarcosine-13C3 (N-Methylglycine-13C3; Sarcosin-13C3) is the 13C-labeled Sarcosine (HY-101037). Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia.
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Org-24598
0 ImagesCat. No.: HY-10712CAS No.: 372198-97-5Org-24598 is an inhibitor of glycine transporter 1 GlyT-1 . Org-24598 can inhibit the specific binding of [3H] CHIBIA-3007 to the rat brain membranes with a Ki value of 16.9 nM.
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GSK931145
0 ImagesCat. No.: HY-111189CAS No.: 896117-64-9GSK931145 is a glycine transporter 1 (GlyT1) inhibitor with anti-epileptic activity. GSK931145 exhibits a low minimum effective dose in the maximum electrical stimulation threshold test, indicating that it has a significant anti-epileptic effect. GSK931145 is also suitable as a positron emission tomography (PET) radioligand for quantifying the availability of glycine transporters in the living brain.
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8-Hydroxyamoxapine
0 ImagesCat. No.: HY-12389CAS No.: 61443-78-5Synonyms: 8-OHAMX8-Hydroxyamoxapine is an orally active antidepressant, which inhibits the reuptake of norepinephrine and serotonin at synapses.
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SSR504734 free base
0 ImagesCat. No.: HY-114895CAS No.: 742693-38-5SSR504734 free base is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 (IC50=18, 15, and 38 nM, respectively). SSR504734 free base shows anti-schizophrenia, anti-anxiety and anti-depression activities.
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ALX-5407
0 ImagesCat. No.: HY-10711CAS No.: 571147-18-7Synonyms: (R)-NFPSALX-5407 ((R)-NFPS) is a selective and orally active glycine transporter GlyT1 inhibitor with an IC50 value of 3 nM. ALX-5407 can be used the research of N-methyl-D-aspartate-receptor function and schizophrenia.
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Stearoyl-L-carnitine chloride-13C3
0 ImagesCat. No.: HY-W770914Stearoyl-L-carnitine chloride-13C3 is the 13C-labeled Stearoyl-L-carnitine chloride (HY-130466). Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM.
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