Influenza Virus
Influenza virus belongs to the Orthomyxoviridae group, which are enveloped, segmented, single-stranded negative sense RNA viruses. The group includes three types of influenza viruses, A, B and C. Type B and C viruses only infect humans, but the type A viruses infect humans, horses, swine, other mammals, and a wide variety of domesticated and wild birds. Human influenza A and B viruses cause seasonal epidemics of disease almost every winter in the United States. The emergence of a new and very different influenza virus to infect people can cause an influenza pandemic. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.
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Influenza Virus Related Products (728)
Related Products (728)
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Recombinant Proteins (585)
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Antibodies (1)
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Rimantadine (Standard)
0 ImagesCat. No.: HY-B0338RCAS No.: 13392-28-4Synonyms: 1-Rimantadine (Standard)Rimantadine (Standard) is the analytical standard of Rimantadine. This product is intended for research and analytical applications. Rimantadine is an orally active inhibitor for M2 protein, that blocks the hydrogen ion channel activity, prevents the entry and replication of the virus, and exhibits board-spectrum antiviral activity.
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Influenza A virus-IN-17
0 ImagesCat. No.: HY-180162CAS No.: 2781933-70-6
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Taurultam
0 ImagesTaurultam is the major active hydrolytic metabolite of Taurolidine (HY-W011522), which selectively activates hTRPA1 to trigger effects in sensory neurons. Taurultam exhibits activity against SARS-CoV-2 variants, influenza A viruses (H1N1, H3N2) and influenza B viruses. Taurultam induces mild tracheal sensory nerve stimulation and CGRP release in mice. Taurultam can be used in studies related to SARS-CoV-2 infection, influenza virus infection, and co-infection with SARS-CoV-2 and influenza A virus.
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RNA polymerase-IN-4
0 ImagesCat. No.: HY-179029CAS No.: 3040910-48-0RNA polymerase-IN-4 is a RNA polymerase inhibitor with an EC50 of 22.81 nM. RNA polymerase-IN-4 exhibits potent anti-influenza virus activity (EC50 = 3.76 nM), relatively low cytotoxicity (CC50 = 29.91 μM). RNA polymerase-IN-4 can be used for the research of infection, such as influenza virus infection.
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RO5464466
0 ImagesCat. No.: HY-120690CAS No.: 1399767-47-5RO5464466 is an hemagglutinin (HA) inhibitor of influenza H1N1 viruses. RO5464466 inhibits HA-mediated hemolysis of chicken erythrocytes with the IC50 of 0.29 μM.
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Favipiravir (Standard)
0 ImagesSynonyms: T-705 (Standard)Favipiravir (Standard) is the analytical standard of Favipiravir. This product is intended for research and analytical applications. Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC50 of 341 nM.
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Fluvirucin B5
0 ImagesCat. No.: HY-N14300CAS No.: 137120-14-0Fluvirucin B5 is an antibiotic against influenza A virus.
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Chloroxylenol (Standard)
0 ImagesChloroxylenol (Standard) is the analytical standard of Chloroxylenol. This product is intended for research and analytical applications. Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses.
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ODE-(S)-HPMPA formate
0 ImagesCat. No.: HY-173595CAS No.: 3032979-17-9ODE-(S)-HPMPA formate is an antiviral compound with strong inhibitory activity against poxviruses and adenoviruses. ODE-(S)-HPMPA formate activates TNF-α secretion.
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PPQ-581
0 ImagesCat. No.: HY-111026CAS No.: 950381-32-5PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation.
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Influenza virus-IN-10
0 ImagesCat. No.: HY-178455CAS No.: 3031321-95-3Influenza virus-IN-10 is a dual-target antiviral agents for influenza that targets both PAC (KD = 8.9 μM) and NP (KD = 52.5 μM) simultaneously. Influenza virus-IN-10 exhibits an EC50 values of 1.64 μM) against influenza A virus (H1N1, A/WSN/33) and broad-spectrum activity against other influenza strains, including influenza B virus and multiple subtypes of influenza A.
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Cap-dependent endonuclease-IN-29
0 ImagesCat. No.: HY-171729CAS No.: 2408318-14-7Cap-dependent endonuclease-IN-29 is a Cap-dependent endonuclease inhibitor and a stereoselective synthetic intermediate. Cap-dependent endonuclease-IN-29 can be used in research on viral infections.
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AEBSF hydrobromide (Standard)
0 ImagesCat. No.: HY-12821RCAS No.: 30827-99-7AEBSF hydrochloride (Standard) is the analytical standard of AEBSF hydrochloride (HY-12821). This product is intended for research and analytical applications. AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
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PAC/NP-IN-1
0 ImagesCat. No.: HY-178366PAC/NP-IN-1 (Compound 30) is a dual-target anti-influenza agent that specifically binds to nucleoprotein (NP) and the C-terminal domain of PA protein (PAc). PAC/NP-IN-1 inhibits influenza A virus A/WSN/33 (H1N1) (EC50 = 3.63 μM, IC50 = 3.08 μM). PAC/NP-IN-1 can be used for the study of influenza infection.
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Fluvirucin B4
0 ImagesCat. No.: HY-N14299CAS No.: 137019-45-5Fluvirucin B4 is an antibiotic against influenza A virus.
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UNC0638 hydrate
0 ImagesCat. No.: HY-110093CAS No.: 1255517-77-1UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 of 15 nM and 19 nM, respectively. UNC0638 hydrate inhibits TNBC cell invasion and migration in vitro. UNC0638 hydrate is also an inhibitor of EHMT1/2 and induces fetal hemoglobin (HbF) expression in human erythroid progenitor cell culture. In addition, UNC0638 hydrate has anti-FMDV (foot-and-mouth disease virus) and anti-VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets.
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Cbz-QFR-kbt
0 ImagesCat. No.: HY-179708CAS No.: 3086979-57-6Cbz-QFR-kbt is a ketone-based benzothiazole ketone inhibitor of TMPRSS2, with an IC50 value of 0.42 nM. Cbz-QFR-kbt also has inhibitory activity against Matriptase, Hepsin, HGFA, and Factor Xa, with IC50 values of 1, 1.3, 85, and 85 nM respectively. Cbz-QFR-kbt shows significant inhibitory effects against SARS-CoV-2 and H1N1 (IC50 = 60 nM). Cbz-QFR-kbt can be used in antiviral research.
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Influenza A virus-IN-15
0 ImagesCat. No.: HY-170646CAS No.: 3075733-28-4Influenza A virus-IN-15 (Compound 9b), a quinoline derivative, is a broad-spectrum inhibitor of influenza A viruses with acceptable cytotoxicity (IC50: 0.88-6.33 μM). Influenza A virus-IN-15 can inhibit the transcription and replication of viral RNA and is used in research for its antiviral effects against influenza A viruses (IAV).
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Cinanserin hydrochloride (Standard)
0 ImagesCat. No.: HY-100943RCAS No.: 54-84-2Synonyms: SQ 10643 (Standard)Cinanserin (hydrochloride) (Standard) is the analytical standard of Cinanserin (hydrochloride) (HY-100943). This product is intended for research and analytical applications. Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
