RSV
Respiratory syncytial virus
RSV (Respiratory syncytial virus) is a leading cause of acute respiratory infections. RSV can exploit host immunity and cause a strong inflammatory response that leads to lung damage and virus dissemination. There is a single RSV serotype with two major antigenic subgroups, A and B.
RSV is a non-segmented negative-sense single-stranded enveloped RNA virus that belongs to the family of Paramyxoviridae, genus Pneumovirus, subfamily Pneumovirinae. Its 10 genes encode 11 proteins since two overlapping open reading frames in the M2 mRNA yield two distinct matrix proteins, M2-1 and M2-2. The viral envelope contains three proteins, the G glycoprotein, the fusion (F) glycoprotein, and the small hydrophobic (SH) protein. The RSV virus comprises five other structural proteins, the large (L) protein, nucleocapsid (N), phosphoprotein (P), matrix (M), and M2-1, and two non-structural proteins (NS1 and NS2).
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RSV Related Products (144)
Related Products (144)
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Recombinant Proteins (11)
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Antibodies (1)
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Ribavirin (GMP)
0 ImagesCat. No.: HY-B0434GCAS No.: 36791-04-5Synonyms: Ribasphere (GMP); ICN-1229 (GMP)Ribavirin (GMP) is Ribavirin (HY-B0434) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV, HIVl, and RSV. Ribavirin also has anti-orthopoxvirus and anti-variola activities.
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Cyclopiazonic acid (Standard)
0 ImagesCat. No.: HY-N6771RCAS No.: 18172-33-3Ancitabine (hydrochloride) (Standard) is the analytical standard of Ancitabine (hydrochloride). This product is intended for research and analytical applications. 0
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RSV-IN-6
0 ImagesCat. No.: HY-150547CAS No.: 2415152-41-7RSV-IN-6 (Compound 53) is an anti-RSV agent targeting M2-1 protein with EC50 values of 4.4 μM and 1.3 μM against RSV-A and RSV-B strain, respectively.
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4-Methoxycinnamaldehyde (Standard)
0 ImagesSynonyms: p-Methoxycinnamaldehyde (Standard)4-Methoxycinnamaldehyde (Standard) is the analytical standard of 4-Methoxycinnamaldehyde. This product is intended for research and analytical applications. 4-Methoxycinnamaldehyde (p-Methoxycinnamaldehyde), an active constituent of Agastache rugosa, exhibits cytoprotective activity against respiratory syncytial virus (RSV) in human larynx carcinoma cell line. 4-Methoxycinnamaldehyde effectively inhibits cytopathic effect of RSV with an estimated IC50 of 0.055 μg/mL[1].
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RSV L-protein-IN-5
0 ImagesCat. No.: HY-154968CAS No.: 851658-28-1RSV L-protein-IN-5 (compound E) is a potent inhibitor of Respiratory syncytial virus (RSV) (EC50=0.1 μM). RSV L-protein-IN-5 inhibits Polymerase (IC50=0.66 μM)，and blocks RSV mRNA synthesis by inhibiting guanylation of viral transcripts. RSV L-protein-IN-5 shows moderate cytotoxicity (CC50=10.7 μM，HEp-2)，also exhibits activity and lowers virus titers in mouse models of RSV infection.
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RSV-IN-5
0 ImagesCat. No.: HY-146108CAS No.: 2415018-86-7RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM).
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Genkwanol C
0 ImagesCat. No.: HY-N10920CAS No.: 151283-11-3
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Glasmacinal
0 ImagesCat. No.: HY-159843CAS No.: 2097822-02-9Synonyms: EP395Glasmacinal is a non-antibacterial macrolide agent with anti-inflammatory activity.
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Amentoflavone (Standard)
0 ImagesAmentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase.
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GS-7682
0 ImagesCat. No.: HY-161877CAS No.: 2694736-39-3GS-7682 is an antiviral compound. GS-7682 has inhibitory activity against pneumoviruses and picornaviruses. GS-7682 can be used in the study of respiratory diseases such as asthma and chronic obstructive pulmonary disease.
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VIR-8190
0 ImagesCat. No.: HY-P991495VIR-8190 is a human IgG1 monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. VIR-8190 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
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Oleoside dimethylester
0 ImagesCat. No.: HY-N9574CAS No.: 30164-95-5Oleoside dimethylester is a secoiridoid glucoside found in the fruits of Ligustrum lucidum. Oleoside dimethylester exhibits inhibitory activity against type 3 parainfluenza virus (Para 3) and respiratory syncytial virus (RSV), with IC50 values of 20.8 and 83.2 μg/mL. Oleoside dimethylester also shows antioxidant effect.
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ent-11β-Hydroxyatis-16-ene-3,14-dione
0 ImagesCat. No.: HY-N3811CAS No.: 1092103-22-4ent-11β-Hydroxyatis-16-ene-3,14-dione (compound 11) is a diterpenoid from the fresh roots of Euphorbia jolkinii. ent-11β-Hydroxyatis-16-ene-3,14-dione has anti-RSV activity.
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Rengynic acid
0 ImagesCat. No.: HY-N1522CAS No.: 517883-38-4
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ASF-006 sodium
0 ImagesCat. No.: HY-179634ASF-006 sodium, a tetrapodal tryptophan derivative, is a potent viral invasion inhibitor. ASF-006 sodium shows potent antiviral activity against different SARS-CoV-2 Omicron variants but not against the ancestral SARS-CoV.2 strain (Wuhan-Hu-1). ASF-006 sodium competitively inhibits receptor-binding domain (RBD)-ACE2 binding via an allosteric mechanism. ASF-006 sodium inhibits Omicron BA.1, Omicron XBB.1.5, respiratory syncytial virus (RSV) and Ebola virus infection with IC50s of 0.02 μM, 0.3 μM, 1.52 μM and 0.2 μM, respectively. ASF-006 sodium inhibits cell entry of both HIV and enterovirus A71[1].
