2. Signaling Pathways
  3. Membrane Transporter/Ion Channel
  4. VDAC
  5. VDAC Isoform

VDAC

 

VDAC Related Products (5):

Cat. No. Product Name Effect Purity
  • HY-111217
    AKOS-22
    		Inhibitor 99.23%
    AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction.
  • HY-109140
    Tuvatexib
    		Modulator 99.36%
    Tuvatexib is an antineoplastic agent.
  • HY-135571
    VBIT-3
    		Inhibitor
    VBIT-3 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 31.3 μM. VBIT-3, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases.
  • HY-176212
    Ferroptosis-IN-20
    		Inhibitor
    Ferroptosis-IN-20 (Compound 34a) is a Ferroptosis inhibitor (EC50: 24.2 nM) targeting voltage-dependent anion channel (VDAC). Ferroptosis-IN-20 inhibits VDAC oligomerization and lipid peroxidation. Ferroptosis-IN-20 reduces content of ROS, attenuates TFR1-mediated iron uptake, inhibits Fe2+ level and restores glutathione (GSH) level. Ferroptosis-IN-20 alleviates Folic acid (HY-16637)-induced acute kidney injury (AKI).
  • HY-108937R
    NSC 15364 (Standard)
    		Inhibitor
    NSC 15364 (Standard) is the analytical standard of NSC 15364 (HY-108937). This product is intended for research and analytical applications. NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis.