2. Signaling Pathways
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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137162
    Dotarizine
    Dotarizine is a novel Piperazine (HY-B0912) derivative and antimigraine agent. Dotarizine exhibits Ca2+ channel blocking properties. Dotarizine decreases the release of lactate dehydrogenase. Dotarizine shows 5-HT receptor blocking effect.
    Dotarizine
  • HY-N15388
    Hericenone A
    Hericenone A is an isoindolinone found in the fruiting bodies of Hericium erinaceus. Hericenone A exerts cytotoxic activity against cancer cells. Hericenone A can be used for the research of cancer, such as metastatic human hepatocellular carcinoma.
    Hericenone A
  • HY-W835723
    1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
    		98.75%
    1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one is a phenolic compound derived from Dracaena cochinchinensis that exhibits antioxidant, antimicrobial, antiviral, hemostatic, antithrombotic, anti-inflammatory activities, and protects myocardial cells.
    1-(2,6-Dimethoxyphenyl)-3-(4-hydroxyphenyl)propan-1-one
  • HY-W614122
    4-((Carboxymethyl)amino)benzoic acid
    4-((Carboxymethyl)amino)benzoic acid (4-COOH-Hippuric acid) is a derivative of 4-Aminobenzoic acidchorismate (PABA) (HY-B1008). 4-((Carboxymethyl)amino)benzoic acid is a competitive inhibitor of 4-Amino-4-deoxychorismate synthase.
    4-((Carboxymethyl)amino)benzoic acid
  • HY-129865
    MET oxalate
    MET oxalate is s a tryptamine.
    MET oxalate
  • HY-W181871
    Piperidione
    Piperidione is a cough agent.
    Piperidione
  • HY-W145571
    3A-Amino-3A-deoxy-(2AS,3AS)-γ-cyclodextrin
    3A-Amino-3A-deoxy-(2AS,3AS)-gamma-cyclodextrin is a derivative of γ-Cyclodextrin (HY-W040040).
    3A-Amino-3A-deoxy-(2AS,3AS)-γ-cyclodextrin
  • HY-101483R
    Dihydromunduletone (Standard)
    Dihydromunduletone (Standard) is the analytical standard of Dihydromunduletone (HY-101483). This product is intended for research and analytical applications. Dihydromunduletone (DHM) is a rotenoid derivative and a selective, potent adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonist with an IC 50 of 20.9 μM for GPR56, but not inhibit GPR110 or class A GPCRs.
    Dihydromunduletone (Standard)
  • HY-172856
    Δ8-Iso-THC acetate
    Δ8-Iso-THC acetate is a phytocannabinoid analogue.
    Δ8-Iso-THC acetate
  • HY-135448
    25G-NBOMe hydrochloride
    25G-NBOMe hydrochloride is a derivative of 2,5-phenethylamines, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine.
    25G-NBOMe hydrochloride
  • HY-W286414
    N,N-dimethyl-N'-p-tolylsulfamide
    N,N-dimethyl-N'-p-tolylsulfamide (DMST) is a hydrolysis product of Tolylfluanid (HY-W774955). The photodegradation rate of N,N-dimethyl-N'-p-tolylsulfamide in coastal seawater is higher than that in seawater or deionized water.
    N,N-dimethyl-N'-p-tolylsulfamide
  • HY-N10337
    Norjuziphine
    Norjuziphine ((-)-Norjuziphine) is an alkaloid found in the lotus flower (Nelumbo nucifera). Norjuziphine inhibits the melanogenesis of murine B16 melanoma 4A5 cells stimulated by Theophylline (HY-B0809) (IC50=14.4 μM). Norjuziphine is promising for research of skin whitening and related skin pigmentation diseases.
    Norjuziphine
  • HY-W770773
    Bosutinib N-Oxide
    Bosutinib N-Oxide (Compound 80) is a quinoline-type heterocyclic compound. Bosutinib N-Oxide shows anti-proliferative activity and can be used for research of leukemia.
    Bosutinib N-Oxide
  • HY-156921
    Zibrofusidic acid
    Zibrofusidic acid (24-Bromofusidic acid; TD-1414) is a brominated derivative of Fusidic acid (HY-B1350). Zibrofusidic acid can be combined within the hydrophobic groove formed by the transmembrane helix 1 (TM1) and the transmembrane helix 2 (TM2) of the AcrB protein. Zibrofusidic acid can be used for the research of multidrug efflux pump.
    Zibrofusidic acid
  • HY-177738
    6'Nicotinate Ac4ManNAz
    6'Nicotinate Ac4ManNAz (Compound 2) is a brain-penetrant carbohydrate-neuroactive heteromer conjugating Ac4ManNAz (HY-W728531) and Nicotinic acid (HY-B0143). 6'Nicotinate Ac4ManNAz can be used for the development of glycosylation-regulating agents or diagnostic probes that cross the BBB.
    6'Nicotinate Ac4ManNAz
  • HY-N15182
    4-Trehalosamine
    4-Trehalosamine is a derivative of trehalose with weak antibacterial activity. 4-Trehalosamine shows no toxic effects when injected intravenously into mice at a dose of 625 mg/kg.
    4-Trehalosamine
  • HY-W719011
    N-Propyl buphedrone hydrochloride
    		Control
    N-Propyl buphedrone hydrochloride is a drug derivative.
    N-Propyl buphedrone hydrochloride
  • HY-175108
    Despropionyl 2'-fluoro ortho-fluorofentanyl
    Despropionyl 2'-fluoro ortho-Fluorofentanyl (2'-Fluoro ortho fluoro ANPP; Despropionyl 2'-fluoro o-FF; Despropionyl 2'-fluoro ortho-FF) is opioid compound and can be used for the research of neurological disease.
    Despropionyl 2'-fluoro ortho-fluorofentanyl
  • HY-138873
    (±)-Threo-Isopropylphenidate hydrochloride
    (±)-Threo-Isopropylphenidate hydrochloride is structurally categorized as a phenethylamine.
    (±)-Threo-Isopropylphenidate hydrochloride
  • HY-W188178
    N-Mitrososarcosine
    N-Nitrososarcosine is a nitrosation product of Sarcosine (HY-101037) and can be found in cured meat products. N-Nitrososarcosine (225 mg/kg) induces the formation of metastatic liver carcinomas in mice.
    N-Mitrososarcosine