2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3820):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-103432
    DPP4-In
    DPP4-In is an active compound.
    DPP4-In
  • HY-N16949
    Taberpsychine
    Taberpsychine is a natural alkaloid.
    Taberpsychine
  • HY-113942
    Cycloate
    Cycloate is an active compound.
    Cycloate
  • HY-N13843
    Toddalosin ethyl ether
    Toddalosin ethyl ether is a natural coumarin.
    Toddalosin ethyl ether
  • HY-N3927
    Garcinexanthone A
    Garcinexanthone A is a natural xanthone.
    Garcinexanthone A
  • HY-W978590
    2-Carene
    2-Carene is an active ingredient that can be extracted from Solanum lycopersicum. 2-Carene belongs to monoterpenoid compounds.
    2-Carene
  • HY-122712
    CB-002
    CB-002 is an active molecule that can be used for the study of advanced malignant solid neoplasm.
    CB-002
  • HY-N9817
    Jasamplexoside A
    Jasamplexoside A is a natural iridoid.
    Jasamplexoside A
  • HY-105270
    Tallimustine
    Tallimustine (FCE 24517), a distamycin-A derivative, is an anticancer agent.
    Tallimustine
  • HY-106469
    Taltrimide
    Taltrimide (MY-117), a lipophilic derivative of Taurine (HY-B0351), strongly inhibits the sodium-independent binding of Taurine to synaptic membranes of brain, the effects on the binding of GABA being less pronounced. Taltrimide exhibits definitive anticonvulsive effects in experimental epilepsy models.
    Taltrimide
  • HY-N18335
    Dihydroepideoxyartennuin B
    Dihydroepideoxyartennuin B is a cadinanolide-class sesquiterpene lactone found in the aerial parts of Artemisia annua.
    Dihydroepideoxyartennuin B
  • HY-108409
    Progesterone carboxylic acid
    Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research.
    Progesterone carboxylic acid
  • HY-139068
    Ibuprofen arginine
    Ibuprofen arginine is an orally active L-arginine of Ibuprofen (HY-78131). With rapid absorption and high bioavailability, Ibuprofen arginine can effectively relieve a variety of acute pain, and has little damage to gastric mucosa and is well tolerated. Ibuprofen arginine can be used in research for pain relief.
    Ibuprofen arginine
  • HY-180163
    HSP70-IN-8
    HSP70-IN-8 (Compound 1b) is a HSP70 inhibitor and Alpinetin (HY-N0625A) derivative. HSP70-IN-8 inhibits the expression of HSP70 protein.HSP70-IN-8 exhibits excellent anti-liver cancer activity.
    HSP70-IN-8
  • HY-19172
    349U85 hydrochloride
    349U85 hydrochloride is a vasodilator-cardiotonic agent.
    349U85 hydrochloride
  • HY-19300A
    PNU-142731A
    PNU-142731A is an active compound.
    PNU-142731A
  • HY-177224
    Antitumor agent-205
    Antitumor agent-205 (compound 9), an Ecteinascidin derivative, is an antitumor agent. Antitumor agent-205 exhibits anti-proliferation activity against A549 and HT29 cells , with GI50 values of 16.4 nM for each cell line. Antitumor agent-205 can be used for lung and colon cancer research.
    Antitumor agent-205
  • HY-117439
    (R)-Norverapamil
    (R)-Norverapamil is an active compound.
    (R)-Norverapamil
  • HY-N18018
    Tetrahydroswertianolin
    Tetrahydroswertianolin (Compound 1) is a tetrahydroxyxanthone glycoside that can be isolated from the whole plant of Swertia japonica Makino. Tetrahydroswertianolin reduces the elevated blood ALT levels in mice with immune-induced liver injury and exhibits protective activity against liver injury. Tetrahydroswertianolin can be used in studies related to anthelmintic, antipyretic and immune-induced liver injury.
    Tetrahydroswertianolin
  • HY-P992381
    IBI352g4a
    IBI352g4a is a humanized IgG1 monoclonal antibody targeting PVRIG (Kd = 0.53 nM) and acts as a PVRIG/PVRL2 inhibitor. The anti-tumor effect of IBI352g4a depends on the binding of its Fc region to FcγR. IBI352g4a binds to the extracellular domains of human and cynomolgus monkey PVRIG, and blocks the PVRIG-PVRL2 interaction. IBI352g4a induces NK cell activation, promotes their degranulation and tumor killing. IBI352g4a can be used in the research of gastric cancer.
    IBI352g4a