2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3818):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-126071
    (-)-Mitorubrinic acid
    (-)-Mitorubrinic acid (Mitorubrinic acid) is a polyketide. (-)-Mitorubrinic acid is synthesis by two non-reducing polyketide synthase (PKS) genes (pks12 and pks11) in a sequential manner. (-)-Mitorubrinic is a virulence factor of Penicillium marneffei by improving its intracellular survival in macrophages.
    (-)-Mitorubrinic acid
  • HY-158595
    15(R),19(R)-Hydroxy prostaglandin F2α
    15(R),19(R)-Hydroxy prostaglandin F2α (15(R),19(R)-Hydroxy PGF2α) is an analog of 19(R)-Hydroxy-prostaglandin F2α. 19(R)-Hydroxy-prostaglandin F2α (HY-N7857) is an ω-1 hydroxylase metabolite of PGF2α found in human semen.
    15(R),19(R)-Hydroxy prostaglandin F2α
  • HY-181124
    Idebenone-SS-20
    Idebenone-SS-20 (Idebenone-2S-FrFK-NH2) is a Idebenone (HY-N0303) derivative conjugated to the mitochondria-targeting peptide SS-20. Idebenone-SS-20 shows neuroprotective and anti-inflammatory effects. Idebenone-SS-20 can preserve mitochondrial membrane potential, enhance ATP production, reduce ROS accumulation, maintain mitochondrial morphology and elevate NAD+/NADH ratio. Idebenone-SS-20 confers robust neuroprotection in a murine model of transient middle cerebral artery occlusion. Idebenone-SS-20 can be used for the research of cerebral.
    Idebenone-SS-20
  • HY-120700
    L-682,679
    L-682,679 is an active compound.
    L-682,679
  • HY-169479
    Betulinic glycine amide
    Betulinic glycine amide (compound 5a) is a pentacyclic triterpenoid and derivative of Betulinic acid (HY-10529). Betulinic glycine amide has been used as a precursor in the synthesis of betulinic acid derivatives with anticancer and antiviral activity.
    Betulinic glycine amide
  • HY-117486
    RU 56187
    RU 56187 is an active compound.
    RU 56187
  • HY-163841
    Antitumor agent-181
    Antitumor agent-181 (HJ1) is an anticancer agent. Antitumor agent-181 inhibits tumor cell growth in vivo and in vitro.
    Antitumor agent-181
  • HY-117412
    KCG 1
    KCG 1 is a potent and selective anti-tumor agent that displays anti-prollferative and cytotoxic effects on epithelial tumoral cells.
    KCG 1
  • HY-119466
    Broperamole
    Broperamole is an anti-inflammatory and antipyretic agent. Broperamole has systemic and toical antiinflammatory activity.
    Broperamole
  • HY-106868
    Clinprost
    Clinprost (Isocarbacyclin methyl ester; TEI 9090; TTC 909) is a drug preparation of the stable prostaglandin I(2) analogue clinprost incorporated into lipid microspheres. Clinprost can reduce infarct volume in stroke rats.
    Clinprost
  • HY-N9764
    8-Glucosyl-5,7-dihydroxy-2-isopropylchromone
    8-Glucosyl-5,7-dihydroxy-2-isopropylchromone is a natural phenolic compound.
    8-Glucosyl-5,7-dihydroxy-2-isopropylchromone
  • HY-N16971
    Acrofolione B
    Acrofolione B is a natural phenolic compound.
    Acrofolione B
  • HY-N17554
    Gleditsioside A
    Gleditsioside A is a natural product that can be found in soap tree.
    Gleditsioside A
  • HY-113526
    AR-12463
    AR-12463 is a derivative of Trapidil (HY-B1016). AR-12463 inhibits the conversion of [14C]acetate to cholesterol. AR-12463 significantly reduces the elevation of total cholesterol in rabbit serum and prevents cholesterol incorporation into tissues. AR-12463 can be used to study atherosclerosis.
    AR-12463
  • HY-N17054
    Assiguxanthone B
    Assiguxanthone B is a natural xanthone.
    Assiguxanthone B
  • HY-153818
    Sperm motility agonist-1
    		99.72%
    Sperm motility agonist-1 is a Cambendazole (HY-107483) derivative and sperm motility agonist. Sperm motility agonist-1 increases curvilinear velocity of motile sperm cells. Sperm motility agonist-1 can be used for the research of male infertility.
    Sperm motility agonist-1
  • HY-N16964
    3,3'-di-O-Methylellagic acid 4-(5''-acetyl)-α-L-arabinofuranoside
    3,3'-di-O-Methylellagic acid 4-(5''-acetyl)-α-L-arabinofuranoside is a natural phenolic compound.
    3,3'-di-O-Methylellagic acid 4-(5''-acetyl)-α-L-arabinofuranoside
  • HY-127069
    Methiomeprazine
    Methiomeprazine is an active compound.
    Methiomeprazine
  • HY-N13797
    1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose
    1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose (Compound 12) is a bitter-tasting compound present in the drupes of Prunus maximowiczii.
    1,6,2',6'-O-Tetraacetyl-3-O-trans-p-coumaroylsucrose
  • HY-186195
    Methyl-cudratricusxanthone B
    Methyl-cudratricusxanthone B is a derivative of Xanthone (HY-N0126), and a derivative of Cudratricusxanthone B. Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM.
    Methyl-cudratricusxanthone B