2. Signaling Pathways
  3. GPCR/G Protein
  4. GLP Receptor
  5. GLP Receptor Modulator

GLP Receptor Modulator

GLP Receptor Modulators (4):

Cat. No. Product Name Effect Purity
  • HY-143312A
    V-0219 hydrochloride
    		Modulator
    V-0219 hydrochloride (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 hydrochloride can be used for obesity-associated diabetes research.
  • HY-143312C
    (S)-V-0219
    		Modulator
    (S)-V-0219 is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (S)-V-0219 activates calcium fluxes in HEK cells stably expressing hGLP-1R. (S)-V-0219 ameliorates high glucose levels in mice and inhibits feeding behavior in fasted mice.
  • HY-143312B
    (R)-V-0219
    		Modulator
    (R)-V-0219 is an enantiomer of V-0219 (HY-143312). V-0219 is an orally active and positive allosteric modulator (PAM) of the GLP Receptor-1 (GLP-1R). (R)-V-0219 activates calcium fluxes in HEK cells stably expressing hGLP-1R.
  • HY-143312
    V-0219
    		Modulator
    V-0219 (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 can be used for obesity-associated diabetes research.