Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10875):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-113424AS

1,2-Dioleoyl-sn-glycero-3-phosphocholine-d₉		98.0%
1,2-Dioleoyl-sn-glycero-3-phosphocholine-d₉ is deuterium labeled 1,2-Dioleoyl-sn-glycero-3-phosphocholine. 1,2-Dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid and is commonly used alone, or with other components, in the generation of micelle

HY-113421S

Linoleoyl ethanolamide-d₄		99.2%
Linoleoyl ethanolamide-d4 is a deuterated labeled Linoleoyl ethanolamide. Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1（CB1）and CB2 receptors, and inhibits the binding of ^[3H]CP-55,940 with K_is of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time.

HY-100582S

Ribitol-1-¹³C		99.51%
Ribitol-1-¹³C is the ¹³C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.

HY-W015882S

4-Methylpentanoic acid-d₁₂		99.25%
4-Methylpentanoic acid-d₁₂ (Isocaproic Acid-d₁₂) is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism.

HY-B0176AS1

(±)-cis-Sertraline-d₃ hydrochloride		99.54%
(±)-cis-Sertraline-d₃ (hydrochloride) is the deuterium labeled Sertraline hydrochloride. Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline hydrochloride is researched for a number of diseases, such as major depressive disorder and obsessive.

HY-16637S

Folic acid-d₂
Folic acid-d₂ (Vitamin B9-d₂) is the deuterium labeled Folic acid. Folic acid (Vitamin M; Vitamin B9) is a B vitamin; is necessary for the production and maintenance of new cells, for DNA synthesis and RNA synthesis.

HY-107469S

Pyridoxal-d₃ hydrochloride		98.81%
Pyridoxal-d₃ (hydrochloride) is the deuterium labeled Pyridoxal hydrochloride.

HY-W088065S

Formate-¹³C sodium		98.0%
Formate-¹³C (sodium) is the ¹³C labeled Sodium formate.Sodium formate is a biochemical assay reagent. Sodium formate can react with zinc sources (such as ZnCl₂) on the surface of alpha alumina support to form a zinc oxide layer. Sodium formate acts as a deprotonating agent, promoting the deprotonation of ligands (such as 2-methylimidazole) at high temperatures. Sodium formate provides the required reducing force in the catalytic oxidation of methane to methanol by methane monooxygenase (sMMO) and inhibits further oxidation of methanol.

HY-111095S1

D-(-)-Lactic acid-¹³C		99.9%
D-(-)-Lactic acid-¹³C ((R)-2-Hydroxypropionic acid-¹³C) is a ¹³C-labeled D-Lactic acid. D-(-)-Lactic acid-¹³C can be used as an internal standard and can also be used in studies such as metabolic tracing.

HY-B0279S

Ramipril-d₅		99.9%
Ramipril-d₅ is the deuterium labeled Ramipril. Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.

HY-144354S

S-Benzyl-DL-cysteine-2,3,3-d₃		99.90%
S-Benzyl-DL-cysteine-2,3,3-d₃ is a deuterium labeled Benzylcysteine. Benzylcysteine is an ASCT2 inhibitor that binds to ASCT2 with an apparent Ki of 780 μM. Benzylcysteine inhibit ASCT2 function based on a competitive mechanism, indicating that Benzylcysteine binds to the substrate-binding site of ASCT2.

HY-B0860S

Diuron-d₆		99.50%
Diuron-d₆ is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research.

HY-W017522S2

Adipic acid-d₄		98.0%
Adipic acid-d₄ (Hexanedioic acid-d₄) is the deuterium labeled Adipic acid (HY-W017522). Adipic acid (Hexanedioic acid) is an orally active compound with anti-HSV-1 activity. Adipic acid has low toxicity and can be used as a food additive and a gelling agent. Adipic acid can also be used in the synthesis of lubricants, artificial resins, plastics, etc.

HY-W041895S

DL-Glutamic acid-d₅		99.68%
DL-Glutamic acid-d₅ is the deuterium labeled DL-Glutamic acid. DL-Glutamic acid is the conjugate acid of Glutamic acid, which acts as a fundamental metabolite. Comparing with the second phase of polymorphs α and β L-Glutamic acid, DL-Glutamic acid presents better stability.

HY-A0181S2

Adenosine monophosphate-d₁₂ dilithium
Adenosine monophosphate-d₁₂ (AMP-d₁₂) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.

HY-B0593S

Ceftazidime-d₅
Ceftazidime-d₅ (GR20263-d₅) is the deuterium labeled Ceftazidime (HY-B0593). Ceftazidime (GR20263), an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases.

HY-N5134S2

5'-Guanylic acid-¹⁵N₅ dilithium		99.33%
5'-Guanylic acid-¹⁵N₅ (5'-GMP-¹⁵N₅ dilithium; 5'-guanosine monophosphate-¹⁵N₅) dilithium is ¹⁵N labeled 5'-Guanylic acid (HY-N5134). 5'-Guanylic acid (5'-GMP) is involved in several metabolic disorders, including the AICA-ribosiduria pathway, adenosine deaminase deficiency, adenine phosphoribosyltransferase deficiency (aprt), and the 2-hydroxyglutric aciduria pathway.

HY-W074890S

Palmitoylglycine-d₃₁		99.40%
Palmitoylglycine-d₃₁ is the deuterium labeled Palmitoylglycine.

HY-I0210S

4-Iodoaniline-¹³C₆		99.17%
4-Iodoaniline-¹³C₆ is the ¹³C labeled 4-Iodoaniline (HY-I0210). 4-Iodoaniline is a potent methemoglobin former. 4-Iodoaniline is also an intermediate. 4-Iodoaniline can be used to synthesize glycogen phosphorylase inhibitors. 4-Iodoaniline is used in the research of liver cancer and blood diseases.

HY-W011565S1

3,6-Di-tert-butyl-9H-carbazole-d₂₅
3,6-Di-tert-butyl-9H-carbazole-d₂₅ is a deuterium labeled 3,6-Di-tert-butyl-9H-carbazole.

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