Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11126)
Related Products (11126)
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Esomeprazole-d3 sodium
0 ImagesCat. No.: HY-17021SSynonyms: (S)-Omeprazole-d3 sodium; (-)-Omeprazole-d3 sodiumEsomeprazole-d3 (sodium) is the deuterium labeled Esomeprazole. Esomeprazole ((S)-Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research.
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Flurbiprofen-d4
0 ImagesCat. No.: HY-10582S3Synonyms: dl-Flurbiprofen-d4Flurbiprofen-d4 is deuterated labeled Flurbiprofen (HY-10582). Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer.
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2-Oxobutanoic acid-13C,d1 sodium hydrate
0 ImagesCat. No.: HY-150628SCAS No.: 1049741-69-62-Oxobutanoic acid-13C,d1 sodium hydrate is the deuterium and 13C labeled 2-Oxobutanoic acid sodium hydrate.
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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d9
0 ImagesCat. No.: HY-W040268S1CAS No.: 2747990-85-61,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-d9 is deuterium labeled 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine. 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine is a phospholipid that is a major component of the lipid bilayer that surrounds cells and provides stability to the membrane.
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(Rac)-Finerenone-d5
0 ImagesCat. No.: HY-W950003CAS No.: 2917530-31-3Synonyms: (Rac)-BAY 94-8862-d5(Rac)-Finerenone-d5 ((Rac)-BAY 94-8862-d5) is the deuterium labeled (Rac)-Finerenone (HY-111372A). (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
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Acetylvaline-13C2
0 ImagesCat. No.: HY-W015466S1Acetylvaline-13C2 is the 13C-labeled Acetylvaline (HY-W015466). Acetylvaline is a class of amino acid derivative metabolites. The expression abundance of Acetylvaline is upregulated under heat stress conditions; it participates in the regulation of amino acid biosynthesis, cysteine and methionine metabolic pathways, and mediates the physiological processes of antioxidant defense and energy metabolism reprogramming in Magallana sikamea. Acetylvaline can be released from acetylvalyl-RNA of Turnip Yellow Mosaic Virus (TYMV) by N‑acylaminoacyl‑tRNA hydrolase. Acetylvaline can be used in metabolism-related research.
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Avibactam-13C5,15N sodium
0 ImagesCat. No.: HY-14879S7Synonyms: NXL-104-13C5,15N sodium
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Ipidacrine-d10
0 ImagesCat. No.: HY-W027553S1Synonyms: NIK-247-d9 free baseIpidacrine-d9 (NIK-247-d9 (free base)) is the deuterium labeled Ipidacrine (HY-W027553). Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases.
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Dexamethasone-d5-1
0 ImagesCat. No.: HY-14648S1Synonyms: Hexadecadrol-d5-1; Prednisolone F-d5-1Dexamethasone-d5-1 is deuterium labeled Dexamethasone. Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18 expression on monocytes. Dexamethasone is highly effective in the control of COVID-19 infection. Dexamethasone inhibits production of exosomes containing inflammatory microRNA-155 in lipopolysaccharide-induced macrophage inflammatory responses.
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Picolinafen-d4 (4-Fluorophenyl-d4)
0 ImagesCat. No.: HY-151912SCAS No.: 2469244-77-5Picolinafen-d4 (4-fluorophenyl-d4) is the deuterium labeled Picolinafen.
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Pyridostigmine-d3 bromide
0 ImagesCat. No.: HY-B0207AS1Pyridostigmine-d3 (bromide) is the deuterium labeled Pyridostigmine bromide. Pyridostigmine bromide is a parasympathomimetic and a reversible cholinesterase inhibitor.
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1-Bromo-2,4-difluorobenzene-d3
0 ImagesCat. No.: HY-W009981SCAS No.: 1219803-87-8Synonyms: 2,4-Difluorobromobenzene-d31-Bromo-2,4-difluorobenzene-d3 is the deuterium labeled 1-Bromo-2,4-difluorobenzene.
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Estradiol 3-d3 (β-D-Glucuronide) sodium
0 ImagesCat. No.: HY-W752886Estradiol 3-d3 (β-D-Glucuronide) sodium is the deuterium labeled Estradiol 3-(β-D-Glucuronide) sodium (HY-N7755). Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies.
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4-Bromo-9H-carbazole-d7
0 ImagesCat. No.: HY-W019238SCAS No.: 3007666-34-14-Bromo-9H-carbazole-d7 is the deuterium labeled 4-Bromo-9H-carbazole.
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Eicosapentaenoic acid 1,2,3,4,5-13C5
0 ImagesCat. No.: HY-B0660S1Synonyms: EPA 1,2,3,4,5-13C, FA 20:5-13C5Eicosapentaenoic acid 1,2,3,4,5-13C5 (EPA 1,2,3,4,5-13C, FA 20:5-13C5) is 13C labeled Eicosapentaenoic Acid. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation.
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Levofloxacin-d3 sodium
0 ImagesCat. No.: HY-W744235Levofloxacin-d3 sodium is the deuterium labeled Levofloxacin sodium (HY-B0330C). Levofloxacin ((-)-Ofloxacin) sodium is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin sodium inhibits the DNA gyrase and topoisomerase IV. Levofloxacin sodium can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin sodium shows anti-orthopoxvirus activity.
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Regorafenib N-oxide and N-desmethyl (M5)-d3-1
0 ImagesCat. No.: HY-W709612Synonyms: N-Desmethyl regorafenib N-oxide-d3-1Regorafenib N-oxide and N-desmethyl (M5)-d3-1 (N-Desmethyl regorafenib N-oxide-d3-1) is the deuterium labeled Regorafenib N-oxide and N-desmethyl (M5) (HY-108226). Regorafenib N-oxide and N-desmethyl (M5) (N-Desmethyl regorafenib N-oxide) is an active metabolite of Sorafenib (HY-10201) and can be metabolized by CYP3A4.
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3-(Trifluoromethyl)phenol-d4
0 ImagesCat. No.: HY-W010153SCAS No.: 1219798-47-6Synonyms: α,α,α-Trifluoro-m-cresol-d43-(Trifluoromethyl)phenol-d4 is the deuterium labeled 3-(Trifluoromethyl)phenol.
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1-Chloro-3-(octanoyloxy)propan-2-yl decanoate-13C3
0 ImagesCat. No.: HY-W718035SCAS No.: 2692623-38-21-Chloro-3-(octanoyloxy)propan-2-yl decanoate-13C3 is a glycerolipid.
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(S)-Propiomazine-d6 hydrochloride
0 ImagesCat. No.: HY-U00051AS2(S)-Propiomazine-d6 hydrochloride is deuterium labeled Propiomazine hydrochloride. Propiomazine hydrochloride is an orally active antihistamine agent. Propiomazine hydrochloride is a potent prolactin (PRL) release stimulant, whose effect depends on the antagonism of the dopaminergic system and can inhibit the secretion of luteinizing hormone (LH). Propiomazine hydrochloride is mainly used for anesthesia assistance, mental disorders and anxiety-induced sedation, and can also be used in research related to insomnia.
