2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (10971):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10042R
    Odanacatib (Standard)
    Odanacatib (Standard) is the analytical standard of Odanacatib (HY-10042). This product is intended for research and analytical applications. Odanacatib (MK-0822) is a potent and selective inhibitor of cathepsin K, with an IC50 of 0.2 nM for human cathepsin K.
    Odanacatib (Standard)
  • HY-100965R
    Diphenyleneiodonium chloride (Standard)
    Diphenyleneiodonium chloride (Standard) is the analytical standard of Diphenyleneiodonium chloride (HY-100965). This product is intended for research and analytical applications. Diphenyleneiodonium chloride is a NADPH oxidase (NOX) inhibitor and also functions as a TRPA1 activator with an EC50 of 1 to 3 μM. Diphenyleneiodonium chloride selectively inhibits intracellular reactive oxygen species.
    Diphenyleneiodonium chloride (Standard)
  • HY-106450R
    Binodenoson (Standard)
    Binodenoson (Standard) is the analytical standard of Binodenoson (HY-106450). This product is intended for research and analytical applications. Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.
    Binodenoson (Standard)
  • HY-112301AR
    trans-Pralsetinib (Standard)
    trans-Pralsetinib (Standard) is the analytical standard of trans-Pralsetinib. This product is intended for research and analytical applications. trans-Pralsetinib (trans-BLU-667) is a rearranged during transfection (RET) inhibitor extracted from patent US20170121312A1, Compound Example 129.
    trans-Pralsetinib (Standard)
  • HY-103596R
    Thalidomide-4-OH (Standard)
    Thalidomide-4-OH (Standard) is the analytical standard of Thalidomide-4-OH (HY-103596). This product is intended for research and analytical applications. Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.
    Thalidomide-4-OH (Standard)
  • HY-123689R
    Samidorphan (Standard)
    Samidorphan (Standard) is the analytical standard of Samidorphan. This product is intended for research and analytical applications. Samidorphan (ALKS-33) is an orally active opioid system modulator that has a high affinity for binding with μ‐opioid, κ‐opioid, and δ‐opioid receptors. Samidorphan acts as an antagonist at μ‐opioid receptors and acts as a partial agonist at k-opioid and δ‐opioid receptors. Samidorphan primarily acts as an opioid receptor antagonist in vivo. Samidorphan can improve the behavior of depressed animals.
    Samidorphan (Standard)
  • HY-W099503R
    Heptyl acetate (Standard)
    Heptyl acetate (Standard) is the analytical standard of Heptyl acetate (HY-W099503). This product is intended for research and analytical applications. Heptyl acetate is a Miscellaneous product that can be isolated from the cold-pressed peel oil of Tosa-buntan (Citrus grandis Osbeck forma Tosa).
    Heptyl acetate (Standard)
  • HY-W128350R
    2,4-Diamino-6-piperidinopyrimidine (Standard)
    2,4-Diamino-6-piperidinopyrimidine (Standard) is the analytical standard of 2,4-Diamino-6-piperidinopyrimidine. This product is intended for research and analytical applications.
    2,4-Diamino-6-piperidinopyrimidine (Standard)
  • HY-W013935R
    Bisphenol B (Standard)
    Bisphenol B (Standard) is the analytical standard of Bisphenol B. This product is intended for research and analytical applications. Bisphenol B is a close structural analog of Bisphenol A (BPA) (HY-18260). Bisphenol B is a potent, orally active endocrine disruptor (ED). Bisphenol B binds to G protein-coupled estrogen receptor (GPER) (IC50 = 3.3 μM) with higher affinity and agonistic activity than BPA. Bisphenol B promotes GPER mediated cell migration. Bisphenol B exerts estrogenic effects via GPER pathway at nanomolar concentration. Bisphenol B is used in the manufacture of polycarbonate resin with ED properties.
    Bisphenol B (Standard)
  • HY-Y0698R
    Thioacetamide (Standard)
    Thioacetamide (Standard) is the analytical standard of Thioacetamide (HY-Y0698). This product is intended for research and analytical applications. Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model.
    Thioacetamide (Standard)
  • HY-10422R
    AZD-8055 (Standard)
    AZD-8055 (Standard) is the analytical standard of AZD-8055 (HY-10422). This product is intended for research and analytical applications. AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. AZD-8055 inhibits both mTORC1 and mTORC2.
    AZD-8055 (Standard)
  • HY-20004R
    (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole (Standard)
    (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole (Standard) is the analytical standard of (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole. This product is intended for research and analytical applications.
    (R)-5-bromo-3-[(1-methyl-2-pyrrolidinyl)methyl]-1H-indole (Standard)
  • HY-W020755R
    Thiohexam (Standard)
    Thiohexam (Standard) is the analytical standard of Thiohexam. This product is intended for research and analytical applications. Thiohexam is a rubber cure accelerator. Thiohexam is also a known allergen and dermatological sensitizer.
    Thiohexam (Standard)
  • HY-100400AR
    K-604 dihydrochloride (Standard)
    K-604 (dihydrochloride) (Standard) is the analytical standard of K-604 (dihydrochloride). This product is intended for research and analytical applications. K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μM.
    K-604 dihydrochloride (Standard)
  • HY-N0585R
    (Rac)-Norcantharidin (Standard)
    (Rac)-Norcantharidin (Standard) is the analytical standard of (Rac)-Norcantharidin (HY-N0585). This product is intended for research and analytical applications. (Rac)-Norcantharidin ((Rac)-NCTD) is the racemic form of Norcantharidin. Norcantharidin is a demethylated derivative of Cantharidin (HY-N0209) and has antitumor activity.
    (Rac)-Norcantharidin (Standard)
  • HY-133091R
    7-Ethoxycoumarin (Standard)
    7-Ethoxycoumarin (Standard) is the analytical standard of 7-Ethoxycoumarin. This product is intended for research and analytical applications. 7-Ethoxycoumarin is a substrate of cytochrome P450 (CYP450). 7-Ethoxycoumarin has been used for the functional characterization of various CYPs and for the generation of 7-hydroxycoumarin (HY-N0573).
    7-Ethoxycoumarin (Standard)
  • HY-W001117R
    3,5-Dimethoxyphenol (Standard)
    3,5-Dimethoxyphenol is a toxin metabolite, found in human consuming yew leaves.
    3,5-Dimethoxyphenol (Standard)
  • HY-N2166R
    Tomatine (Standard)
    Tomatine is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity.
    Tomatine (Standard)
  • HY-15111R
    2-Acetylbenzothiophene (Standard)
    2-Acetylbenzothiophene (Standard) is the analytical standard of 2-Acetylbenzothiophene. This product is intended for research and analytical applications.
    2-Acetylbenzothiophene (Standard)
  • HY-100080R
    A-887826 (Standard)
    A-887826 (Standard) is the analytical standard of A-887826 (HY-100080). This product is intended for research and analytical applications. A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo.
    A-887826 (Standard)