2. Signaling Pathways
  3. MAPK/ERK Pathway
  4. SOS1
  5. SOS1 Degrader

SOS1 Degrader

SOS1 Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-161233A
    BTX-6654 formate
    		Degrader 98.85%
    BTX-6654 formate is a target-dependent and -specific cereblon-based bifunctional SOS1 PROTAC degrader. BTX-6654 formate reduces downstream signaling markers pERK and pS6, and displays antiproliferative activity in cells harboring various KRAS mutations.
  • HY-161233
    BTX-6654
    		Degrader
    BTX-6654 is a target-dependent and -specific cereblon-based bifunctional SOS1 PROTAC degrader. BTX-6654 reduces downstream signaling markers pERK and pS6, and displays antiproliferative activity in cells harboring various KRAS mutations.