2. Membrane Transporter/Ion Channel
    Neuronal Signaling
  3. Calcium Channel
  4. Trimethadione

Trimethadione (Synonyms: 3,5,5,-Trimethyloxazolidine-2,4-dione)

Cat. No.: HY-A0092 Purity: ≥98.0%
Handling Instructions

Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures. Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects.

For research use only. We do not sell to patients.

Trimethadione Chemical Structure

Trimethadione Chemical Structure

CAS No. : 127-48-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 66 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 60 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
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Description

Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is an oxazolidinedione anticonvulsant agent widely used against absences seizures. Trimethadione also is a T-type calcium channel blocker which has antihyperalgesic effects[1][2].

Molecular Weight

143.14

Formula

C₆H₉NO₃
CAS No.
SMILES

O=C(N1C)OC(C)(C)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 40 mg/mL (279.45 mM)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.9862 mL 34.9308 mL 69.8617 mL
5 mM 1.3972 mL 6.9862 mL 13.9723 mL
10 mM 0.6986 mL 3.4931 mL 6.9862 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Trimethadione3,5,5,-Trimethyloxazolidine-2,4-dioneCalcium ChannelCa2+ channelsCa channelsanticonvulsantabsencesseizuresT-typecalciumchannelantihyperalgesicInhibitorinhibitorinhibit

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