1. PROTAC
  2. Ligand for E3 Ligase
  3. AhR Ligand 1

AhR Ligand 1 (Synonyms: E3 ligase Ligand 17)

Cat. No.: HY-130269
Handling Instructions

AhR Ligand 1 (E3 ligase Ligand 17) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. AhR Ligand 1 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins .

For research use only. We do not sell to patients.

AhR Ligand 1 Chemical Structure

AhR Ligand 1 Chemical Structure

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All Ligand for E3 Ligase Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

AhR Ligand 1 (E3 ligase Ligand 17) is a ligand for arylhydrocarbon receptor (AhR) E3 ligase. AhR Ligand 1 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs (e.g., β-naphthoflavone-JQ1) that recruit the AhR E3 ligase complex by incorporating AhR ligands into chimeric molecules. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins [1].

IC50 & Target[1]

cIAP1

 

Molecular Weight

302.32

Formula

C₂₀H₁₄O₃

SMILES

O=C1C=C(C2=CC=C(CO)C=C2)OC3=C1C4=CC=CC=C4C=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

AhR Ligand 1E3 ligase Ligand 17AhR Ligand1AhR Ligand-1Ligand for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product name:
AhR Ligand 1
Cat. No.:
HY-130269
Quantity:
MCE Japan Authorized Agent: