1. PI3K/Akt/mTOR
  2. Akt
  3. Akt1-IN-1

Akt1-IN-1 

Cat. No.: HY-146459
Handling Instructions

Akt1-IN-1 (compound 5b) is a potent and selective Akt1 inhibitor with an IC50 value of 18.79 nM in MIA Paca-2 cells. Akt1-IN-1 does not exhibit obvious teratogenicity, hepatotoxicity and cardiotoxicity (No Observed Adverse Effect Level > 100 µM). Akt1-IN-1 can be used for researching anticancer.

For research use only. We do not sell to patients.

Akt1-IN-1 Chemical Structure

Akt1-IN-1 Chemical Structure

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Description

Akt1-IN-1 (compound 5b) is a potent and selective Akt1 inhibitor with an IC50 value of 18.79 nM in MIA Paca-2 cells. Akt1-IN-1 does not exhibit obvious teratogenicity, hepatotoxicity and cardiotoxicity (No Observed Adverse Effect Level > 100 µM). Akt1-IN-1 can be used for researching anticancer[1].

IC50 & Target

IC50: 18.79 nM in MIA Paca-2 cells[1]

Molecular Weight

639.76

Formula

C31H34FN5O5S2

SMILES

CC1=CC=C(C=C1)S(=O)(N2C(COCC3=C(N=C(N=C3C(C)C)N(S(C)(=O)=O)C)C4=CC=C(CC4)F)=CC5=CN=CC=C52)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Akt1-IN-1
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HY-146459
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