ALG-000184
Based on 1 Customer Validation
ALG-000184 is an orally effective inhibitor of hepatitis B virus (HBV), and it is also a prodrug of ALG-001075 (HY-177022). ALG-000184 can inhibit the production of HBV DNA in liver cells. ALG-000184 can be used in the research of chronic hepatitis B.
For research use only. We do not sell to patients.
- Purity: 99.08%
- CAS No.: 2495324-72-4
- Formula: C23H20FN4Na2O8P
- Molecular Weight:576.38
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
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Drug Repurposing Compound Library Plus
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Clinical Compound Library Plus
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Alkyne Compound Library
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All DNA/RNA Synthesis Isoforms
More
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2495324-72-4
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Appearance Solid
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Molecular Weight 576.38
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Formula C23H20FN4Na2O8P
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Color White to light yellow
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SMILES
CC1=C(C(NC2=CC=C(F)C(C#N)=C2)=O)N(C)C(C)=C1C(C(N(C3(C#C)COC3)COP(O[Na])(O[Na])=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 116.67 mg/mL (202.42 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.7350 mL | 8.6748 mL | 17.3497 mL | 43.3742 mL |
| 5 mM | 0.3470 mL | 1.7350 mL | 3.4699 mL | 8.6748 mL | |
| 10 mM | 0.1735 mL | 0.8675 mL | 1.7350 mL | 4.3374 mL | |
| 15 mM | 0.1157 mL | 0.5783 mL | 1.1566 mL | 2.8916 mL | |
| 20 mM | 0.0867 mL | 0.4337 mL | 0.8675 mL | 2.1687 mL | |
| 25 mM | 0.0694 mL | 0.3470 mL | 0.6940 mL | 1.7350 mL | |
| 30 mM | 0.0578 mL | 0.2892 mL | 0.5783 mL | 1.4458 mL | |
| 40 mM | 0.0434 mL | 0.2169 mL | 0.4337 mL | 1.0844 mL | |
| 50 mM | 0.0347 mL | 0.1735 mL | 0.3470 mL | 0.8675 mL | |
| 60 mM | 0.0289 mL | 0.1446 mL | 0.2892 mL | 0.7229 mL | |
| 80 mM | 0.0217 mL | 0.1084 mL | 0.2169 mL | 0.5422 mL | |
| 100 mM | 0.0173 mL | 0.0867 mL | 0.1735 mL | 0.4337 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
ALG-000184 Related Classifications
HY-169993 Related Classifications
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