Anti-Mouse CD18 Antibody (M18/2)
Based on 1 Customer Validation
Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD18. Anti-Mouse CD18 Antibody (M18/2) can neutralize lymphocyte function-associated antigen 1 (LFA-1). Anti-Mouse CD18 Antibody (M18/2) can be used for the researches of immunology, such as heart transplantation.
For research use only. We do not sell to patients.
- Purity: ≥95.0%
- Molecular Weight:150 kDa
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Rat IgG2a kappa
Mouse
CD18
Anti-Mouse CD18 Antibody (M18/2) (2.5 µg/well, 1-2 days) does not inhibit lymphocyte function-associated antigen 1 (LFA-1)-mediated clusters in OT-I T cells[1].
Anti-Mouse CD18 Antibody (M18/2) (10 µg/mL, 5 h) enhances murine procoagulant response.in Peritoneal exudate cells[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
Product Image
in vivo Neutralization & Blocking
Chemical Information
-
Appearance Liquid
-
Molecular Weight 150 kDa
-
Color Colorless to light yellow
-
SMILES
[Anti-Mouse CD18 Antibody (M18/2)]
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
-
Data Sheet (258 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Inhibitory Antibodies User Guide (603 KB)
References
[1]. Zumwalde NA, et al. ICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation. J Immunol. 2013 Oct 1;191(7):3681-93. [Content Brief]
[2]. Isobe M, et al. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science. 1992 Feb 28;255(5048):1125-7. [Content Brief]
[3]. Fan ST, et al. Coupling of the adhesive receptor CD11b/CD18 to functional enhancement of effector macrophage tissue factor response. J Clin Invest. 1991 Jan;87(1):50-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse CD18 Antibody (M18/2) Related Classifications
HY-P990288 Related Classifications
Powered by Bioz