Antibacterial agent 136
Antibacterial agent 136 (compound 3) is an antibiotic of oxadiazolones. Antibacterial agent 136 have high antibacterial potency against Staphylococcus aureus (MRSA) with a MIC50 value of 0.8 μM.
For research use only. We do not sell to patients.
- Formula: C23H19N3O5
- Molecular Weight:417.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
MIC50: 0.8 μM (MRSA)[1]
In Vitro
Antibacterial agent 136 (compound 3) have high antibacterial potency against Staphylococcus aureus (MRSA) with a MIC50 value of 0.8 μM[1].
Antibacterial agent 136 have high antibacterial potency against multidrug-resistant S. aureus with MIC50 values range from 0.8 -3.1 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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Molecular Weight 417.41
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Formula C23H19N3O5
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SMILES
COC1=NN(C(O1)=O)C2=CC=C(C(C)=C2)NC(C3=CC(OC4=CC=CC=C4)=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antibacterial agent 136 Related Classifications
HY-148576 Related Classifications
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