2. Cell Cycle/DNA Damage Membrane Transporter/Ion Channel
  3. Topoisomerase GLUT
  4. Antitumor agent-102

Antitumor agent-102 (compound 10) is a conjugate of Topoisomerase I inhibitor SN38 and glucose transporter inhibitor, targeting to colorectal cancer. Antitumor agent-102 induces higher concentrations of free SN38 in tumor tissues than Irinotecan (HY-16562).

For research use only. We do not sell to patients.

Antitumor agent-102 Chemical Structure

Antitumor agent-102 Chemical Structure

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Antitumor agent-102 Related Antibodies

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Description

Antitumor agent-102 (compound 10) is a conjugate of Topoisomerase I inhibitor SN38 and glucose transporter inhibitor, targeting to colorectal cancer. Antitumor agent-102 induces higher concentrations of free SN38 in tumor tissues than Irinotecan (HY-16562)[1].

Molecular Weight

1355.51

Formula

C70H82N8O18S
SMILES

O=C(N1CCCCC(N[C@H](C(N[C@H](C(NC2=CC=C(C=C2)COC3=CC=C(C4=C3)N=C5C(N6CC5=C4CC)=CC([C@@](CC)7O)=C(C6=O)COC7=O)=O)CCCNC(N)=O)=O)C(C)C)=O)C(SCCOCCOCCOC8=CC(O)=C(C(O)=C8)C(CCC9=CC=C(C=C9)O)=O)CC1=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Antitumor agent-102 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-102Antitumor agent102Antitumor agent 102TopoisomeraseGLUTGlucose transporterInhibitorinhibitorinhibit

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