Apidaecin IA acetate
Based on 1 Customer Validation
Apidaecin IA acetate is a basic peptide. Apidaecin IA acetate inhibits the enzymatic activity of DnaK. Apidaecin IA acetate induces bacterial cell death. Apidaecin IA acetate can be used in research related to peritonitis and bacterial infections.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C95H150N32O23·xC2H4O2
- Molecular Weight:2108.41 (free base)
-
Speicherung:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
DnaK |
In Vitro
Apidaecin IA (100 ng/mL; 8 h) acetate inhibits DnaK activity and binds LPS (HY-D1056), reducing bacterial survival by approximately 2 log10 at 8 h post-induction[1].
Apidaecin IA (0.02-200 μg/mL) acetate potently inhibits the growth of a variety of Gram-negative bacterial strains, with its MIC values ranging from 0.02 μg/mL to 0.2 μg/mL[2].
Apidaecin IA (100 μg/mL) acetate exhibits antibacterial activity against Escherichia coli NCTC 9001 cells. It inhibits the growth of the cells without causing immediate lysis, and does not interfere with the phospholipid bilayer[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 2108.41 (free base)
-
Formel C95H150N32O23·xC2H4O2
-
Sequence
Gly-Asn-Asn-Arg-Pro-Val-Tyr-Ile-Pro-Gln-Pro-Arg-Pro-Pro-His-Pro-Arg-Ile
-
Sequence Shortening
GNNRPVYIPQPRPPHPRI
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 5 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)