Apidaecin IA acetate
Based on 1 Customer Validation
Apidaecin IA acetate is a basic peptide. Apidaecin IA acetate inhibits the enzymatic activity of DnaK. Apidaecin IA acetate induces bacterial cell death. Apidaecin IA acetate can be used in research related to peritonitis and bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C95H150N32O23·xC2H4O2
- 分子量:2108.41 (free base)
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
IC50 & Target
[1]|
DnaK |
体外実験
Apidaecin IA (100 ng/mL; 8 h) acetate inhibits DnaK activity and binds LPS (HY-D1056), reducing bacterial survival by approximately 2 log10 at 8 h post-induction[1].
Apidaecin IA (0.02-200 μg/mL) acetate potently inhibits the growth of a variety of Gram-negative bacterial strains, with its MIC values ranging from 0.02 μg/mL to 0.2 μg/mL[2].
Apidaecin IA (100 μg/mL) acetate exhibits antibacterial activity against Escherichia coli NCTC 9001 cells. It inhibits the growth of the cells without causing immediate lysis, and does not interfere with the phospholipid bilayer[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Solid
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分子量 2108.41 (free base)
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分子式 C95H150N32O23·xC2H4O2
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配列
Gly-Asn-Asn-Arg-Pro-Val-Tyr-Ile-Pro-Gln-Pro-Arg-Pro-Pro-His-Pro-Arg-Ile
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シーケンスの短縮
GNNRPVYIPQPRPPHPRI
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 5 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)