p38α-IN-13
p38α-IN-13 is p38α MAPK, BChE and AChE inhibitor with IC50 values of 5.79, 16.24, 51.8 µM for p38α MAP, hBChE, hAChE, respectively. p38α-IN-13 has the potential for the research of Alzheimer’s disease.
For research use only. We do not sell to patients.
- CAS No.: 3077831-12-7
- Formula: C22H26F2N4O2
- Molecular Weight:416.46
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
p38α MAPK 5.79 μM (IC50) |
hBCHE 16.24 μM (IC50) |
hAChE 51.8 μM (IC50) |
p38α-IN-13 (5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-2-isobutyl-2H-indazole-6-carboxamide) is a p38α MAPK, BChE and AChE inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 3077831-12-7
-
Molecular Weight 416.46
-
Formula C22H26F2N4O2
-
SMILES
O=C(C1=CC2=NN(CC(C)C)C=C2C=C1OC3=CC=C(F)C=C3F)NCCN(C)C
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
p38α-IN-13 Related Classifications
HY-114422 Related Classifications
Powered by Bioz