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Art. -Nr.: HY-N20636

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7α-Morroniside

7α-Morroniside is a STAT3 promoter inhibitor. 7α-Morroniside inhibits IL-6-induced STAT3 promoter activity in hepatocellular carcinoma cells. 7α-Morroniside can be used for the research of inflammation-related diseases.

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CAS. Nr.: 61849-88-5
Formel: C₁₇H₂₆O₁₁
Molecular Weight:406.38

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

7α-Morroniside Chemical Structure

CAS. Nr.: 61849-88-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Calculators
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Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

STAT3

Alle STAT Isoform-spezifische Produkte anzeigen :

In Vitro

7α-Morroniside (Compound 22) (7 μM; 1 h pre-incubation + 6 h co-incubation with IL-6) potently inhibits IL-6-induced STAT3 promoter activity in HepG2 cells, with an IC₅₀ of 7 μM, and shows no cytotoxicity at effective concentrations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 61849-88-5
Molecular Weight 406.38
Formel C₁₇H₂₆O₁₁
SMILES

COC(C1=CO[C@H]([C@@]2([H])[C@]1([H])C[C@H](O[C@H]2C)O)O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)=O
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Ye XS, et al.. Cornusides A-O, Bioactive Iridoid Glucoside Dimers from the Fruit of Cornus officinalis. Journal of natural products. 2017 Dec 22;80(12):3103-3111. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
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- In Vitro
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7α-Morroniside

Alle STAT Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

7α-Morroniside Related Classifications

HY-N20636 Related Classifications