CHF-6550
CHF-6550 is an antagonist for muscarinic M3 receptor and an agonist for β2 adrenoceptor (MABA), with pKi of 9.3 and 10.6, respectively. CHF-6550 exhibits good hepatocyte clearance in rat models and good pharmacokinetic characteristics in guinea pigs.
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- CAS. Nr.: 3052116-62-5
- Formel: C42H46N4O8
- Molecular Weight:734.84
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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β2 adrenoceptor 10.6 (pKi) |
mAChR3 9.3 (pKi) |
Chemical Information
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CAS. Nr. 3052116-62-5
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Molecular Weight 734.84
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Formel C42H46N4O8
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SMILES
O=C(C1=CC=C(C=C1)CNC[C@H](O)C2=C3C=CC(NC3=C(C=C2)O)=O)NCCCOC4=CC=CC([C@](O)(C(O[C@H]5CN(CCC5)C)=O)C6=CC=CC=C6)=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)