D-Allothreonine
Based on 1 Customer Validation
D-Allothreonine is the D stereoisomer of Allothreonine. D-Allallreonine is a peptide lipid derived from bacteria. D-Allothreonine can be specifically oxidized by D-amino acid oxidase, while the L configuration has no reaction. D-Allallreonine is also a component of bacterial polysaccharides. D-Allallreonine can be used for researching bacterial pathogenicity, antigenic diversity and drug resistance.
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- Reinheit: 98.0%
- CAS. Nr.: 24830-94-2
- Formel: C4H9NO3
- Molecular Weight:119.12
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Microbial Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
>100 μg/mL
Compound: F2-Thr (2R,3R)
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Tested for the effect of stereochemistry on the growth of L1210 mouse leukemia cell line in vitro
Tested for the effect of stereochemistry on the growth of L1210 mouse leukemia cell line in vitro
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10.1016/S0960-894X(01)81041-6 |
Chemical Information
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CAS. Nr. 24830-94-2
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Appearance Solid
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Molecular Weight 119.12
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Formel C4H9NO3
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Color White to off-white
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SMILES
N[C@H]([C@H](O)C)C(O)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
H2O : 25 mg/mL (209.87 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 8.33 mg/mL (69.93 mM); Clear solution; Need ultrasonic and warming and heat to 60°C
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. M IKAWA, et al. Occurrence of D-phenylalanine, D-allothreonine and Other D-amino-acids in Peptido-Lipids of Bacterial Origin. Nature. 1960 Nov 12;188:558-60. [Content Brief]
[2]. C Petersson, et al. Structural Studies of the O-specific Polysaccharide of Hafnia Alvei Strain PCM 1206 Lipopolysaccharide Containing D-allothreonine. Eur J Biochem. 1997 Mar 1;244(2):580-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.3949 mL | 41.9745 mL | 83.9490 mL | 209.8724 mL |
| 5 mM | 1.6790 mL | 8.3949 mL | 16.7898 mL | 41.9745 mL | |
| 10 mM | 0.8395 mL | 4.1974 mL | 8.3949 mL | 20.9872 mL | |
| 15 mM | 0.5597 mL | 2.7983 mL | 5.5966 mL | 13.9915 mL | |
| 20 mM | 0.4197 mL | 2.0987 mL | 4.1974 mL | 10.4936 mL | |
| 25 mM | 0.3358 mL | 1.6790 mL | 3.3580 mL | 8.3949 mL | |
| 30 mM | 0.2798 mL | 1.3991 mL | 2.7983 mL | 6.9957 mL | |
| 40 mM | 0.2099 mL | 1.0494 mL | 2.0987 mL | 5.2468 mL | |
| 50 mM | 0.1679 mL | 0.8395 mL | 1.6790 mL | 4.1974 mL | |
| 60 mM | 0.1399 mL | 0.6996 mL | 1.3991 mL | 3.4979 mL | |
| 80 mM | 0.1049 mL | 0.5247 mL | 1.0494 mL | 2.6234 mL | |
| 100 mM | 0.0839 mL | 0.4197 mL | 0.8395 mL | 2.0987 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.