DEL-C1
DEL-C1 is a CHI3L1 inhibitor. DEL-C1 can restore the ability to clear Amyloid-β and repair lysosomal function of astrocytes. DEL-C1 can inhibit NF-κB signaling and IL-6 secretion. DEL-C1 can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C38H45N7O4S
- Molecular Weight:695.87
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
DEL-C1 (5-25 μM, 30 mins) restores the CHI3L1-induced decrease in Aβ1-42 uptake in human iPSC-derived astrocytes[1].
DEL-C1 (5-25 μM, 30 mins) improves the CHI3L1-inhibited lysosomal degradation of DQ-BSA in the astrocytes[1].
DEL-C1 (5-25 μM, 30 mins) inhibits CHI3L1-driven secretion of CHI3L1 and IL-6 and activation of NF-κB in the astrocytes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 695.87
-
Formel C38H45N7O4S
-
SMILES
CNC(C[C@H](C1=CC=CC=C1)NC(C[C@@H](NC([C@@H]2CCCC[C@H]2NCC3=CN=C(O3)C4=C(N=C(S4)C)C)=O)CC5=CNC6=C5C=CC=C6)=O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DEL-C1 Related Classifications
HY-179214 Related Classifications
Powered by Bioz