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Art. -Nr.: HY-182714

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N 0840

(Synonyms: N6-Cyclopentyl-9-methyladenine)

N 0840 is a neutral antagonist of adenosine A₁ receptor (A₁AR), with a K_i value of 279 nM in rats and 1185 nM in humans. N 0840 modulates adenosine A₁ receptor to increase forskolin-induced cyclic 3′,5′-adenosine monophosphate production, with a GTP shift value close to 1. N 0840 can be used in studies of neuroprotection, cardiovascular/renal function^[1].

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CAS. Nr.: 109292-91-3
Formel: C₁₁H₁₅N₅
Molecular Weight:217.27

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

N 0840 Chemical Structure

CAS. Nr.: 109292-91-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Beschreibung

Alle Adenosine Receptor Isoform-spezifische Produkte anzeigen :

In Vitro

N 0840 binds to rat cortical membrane adenosine A₁ receptors with a K_i of 279 nM, and exhibits a GTP shift of 0.94^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 109292-91-3
Molecular Weight 217.27
Formel C₁₁H₁₅N₅
SMILES

CN1C=NC2=C1N=CN=C2NC3CCCC3
Synonyms

N6-Cyclopentyl-9-methyladenine
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Van Calenbergh S, et al. 5 ‘-Deoxy Congeners of 9-(3-Amido-3-deoxy-β-d-xylofuranosyl)-N 6-cyclopentyladenine: New Adenosine A1 Receptor Antagonists and Inverse Agonists. Journal of medicinal chemistry. 2002 Apr 25;45(9):1845-52.

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Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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N 0840

Alle Adenosine Receptor Isoform-spezifische Produkte anzeigen

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N 0840 Related Classifications

HY-182714 Related Classifications