PF-04677490
PF-04677490 is a PDE1 inhibitor (IC50: 21 nM). PF-04677490 has IC50s of 21 nM, 83 nM, and 118 nM for PDE1B1, PDE1C, and PDE1A, respectively. PF-04677490 efficaciously inhibits cAMP- and cGMP-hydrolytic activity.
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- CAS. Nr.: 1628342-10-8
- Formel: C17H21N5O2
- Molecular Weight:327.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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PDE1B 21 nM (IC50) |
PDE1C 83 nM (IC50) |
PDE1A 118 nM (IC50) |
Chemical Information
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CAS. Nr. 1628342-10-8
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Molecular Weight 327.38
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Formel C17H21N5O2
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SMILES
CC(CC1=NNC(C)=C1)NC2=C3C=CC(OC)=C(C3=NC=N2)OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)