PMED-1
PMED-1 is a β-catenin inhibitor that significantly reduces β-catenin activity in hepatoblastoma cells and various HCC cells, with an IC50 value ranging from 4.87 to 32 μM. PMED-1 affects Wnt signaling by decreasing the interaction between β-catenin and CREB binding protein, thereby inhibiting cell proliferation. PMED-1 has potential applications in cancer research.
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- CAS. Nr.: 491828-75-2
- Formel: C20H18FN3O
- Molecular Weight:335.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 491828-75-2
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Molecular Weight 335.37
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Formel C20H18FN3O
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SMILES
O=C(NC1=CN(CC2=CC=C(F)C=C2)N=C1)C(C3)C3C4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PMED-1 Related Classifications
HY-164520 Related Classifications
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