2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Endogenous Metabolite Antibiotic
  4. Bactofencin A acetate

Bactofencin A acetate is a class IId bacteriocin and Antibacterial agent. Bactofencin A acetate is produced by Lactobacillus salivarius DPC6502, an isolate derived from the intestine. Bactofencin A acetate exhibits activity against Staphylococcus and Listeria species. Bactofencin A acetate slightly modulates the intestinal flora. Bactofencin A acetate can be used in research related to staphylococcal infections, listerial infections, and mastitis.

For research use only. We do not sell to patients.

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Bactofencin A acetate

Bactofencin A acetate Chemical Structure

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Bactofencin A acetate Related Antibodies

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Description

Bactofencin A acetate is a class IId bacteriocin and Antibacterial agent. Bactofencin A acetate is produced by Lactobacillus salivarius DPC6502, an isolate derived from the intestine. Bactofencin A acetate exhibits activity against Staphylococcus and Listeria species. Bactofencin A acetate slightly modulates the intestinal flora. Bactofencin A acetate can be used in research related to staphylococcal infections, listerial infections, and mastitis[1].

IC50 & Target[1]

Microbial Metabolite

 

In Vitro

Bactofencin A (0.25-1000 µM; assay duration at 37 °C) acetate exhibit potent anti-Staphylococcus aureus DPC5246 activity[1].
Bactofencin A (0.25-1000 µM; assay duration at 37 °C) acetate with substitution of Cys7 or Cys22 with serine or alanine significantly reduces anti-Staphylococcus aureus DPC5246 activity, with C22 substitutions causing greater activity loss than C7 substitutions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bactofencin A acetate Related Antibodies
Molecular Weight

2783.29 (free base)

Formula

C119H188N42O28S4·xC2H4O2
Appearance

Solid

Color

White to off-white

Sequence

Lys-Arg-Lys-Lys-His-Arg-Cys-Arg-Val-Tyr-Asn-Asn-Gly-Met-Pro-Thr-Gly-Met-Tyr-Arg-Trp-Cys (Disulfide bridge: Cys7-Cys22)
Sequence Shortening

KRKKHRCRVYNNGMPTGMYRWC (Disulfide bridge: Cys7-Cys22)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL

*"≥" means soluble, but saturation unknown.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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Bactofencin A acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bactofencin ABacterialEndogenous MetaboliteAntibioticInhibitorinhibitorinhibit

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