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Bcl-2-IN-20

Bcl-2-IN-20 (Compound 81) is an inhibitor for Bcl-2 with IC50 <10 μM (79.1% inhibition at 9 μM). Bcl-2-IN-20 exhibits cytotoxicity in SK-MEL-28 (IC50>10 μM), A549 (IC50=6.1 μM), HepG2 (IC50>10 μM), MCF-7 (IC50=8.9 μM), HCT116 (IC50>10 μM) and HEK-293 (IC50=14.1 μM). Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage.

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  • 分子式: C22H14BrNO6S
  • 分子量:500.32
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Bcl-2-IN-20 Chemical Structure
    Bcl-2-IN-20 構造式
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  • Bcl-2-IN-20 Chemical Structure
    Bcl-2-IN-20 Chemical Structure
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  • Bcl-2-IN-20