Bcl-2-IN-20
Bcl-2-IN-20 (Compound 81) is an inhibitor for Bcl-2 with IC50 <10 μM (79.1% inhibition at 9 μM). Bcl-2-IN-20 exhibits cytotoxicity in SK-MEL-28 (IC50>10 μM), A549 (IC50=6.1 μM), HepG2 (IC50>10 μM), MCF-7 (IC50=8.9 μM), HCT116 (IC50>10 μM) and HEK-293 (IC50=14.1 μM). Bcl-2-IN-20 promotes the ROS production, induces apoptosis and DNA damage.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C22H14BrNO6S
- Peso molecular:500.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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Peso molecular 500.32
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Fòrmula C22H14BrNO6S
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SMILES
O=C(/C(S1)=C/C2=COC3=CC=C(Br)C=C3C2=O)N(CC(C4=CC=C(OC)C=C4)=O)C1=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bcl-2-IN-20 Related Classifications
HY-161786 Related Classifications
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