Bcl-2-IN-22
Bcl-2-IN-22 (compound 1) is a gold(I) NHC complex with anticancer activity. Bcl-2-IN-22 induces apoptosis via the mitochondrial pathway with an IC50 value of 0.014 μM. In addition, Bcl-2-IN-22 targets BCL-2 family members and exhibits pro-apoptosis and resensitization properties in multidrug-resistant leukemia cells that overexpress BCL-2.
For research use only. We do not sell to patients.
- Formula: C38H46AuF6N8P
- Molecular Weight:956.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 956.76
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Formula C38H46AuF6N8P
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SMILES
CC1=CC(C)=CC(C)=C1[N]2=NC([Au+]C3N=[N](C4=C(C)C=C(C)C=C4C)N=[N]3C5=C(C)C=C(C)C=C5C)[N](C6=C(C)C=C(C)C=C6C)=N2.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bcl-2-IN-22 Related Classifications
HY-169083 Related Classifications
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