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Cat. No.: HY-172203

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BI-1915

BI-1915, a chemical probe, is the selective inhibitor for Cathepsin S with an IC₅₀ of 17 nM. BI-1915 can be used in research of autoimmune diseases.

For research use only. We do not sell to patients.

The BI-1915 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

CAS No.: 752237-67-5
Formula: C₂₁H₃₇N₅O₃
Molecular Weight:407.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

BI-1915 Chemical Structure

CAS No.: 752237-67-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BI-1915, a chemical probe, is the selective inhibitor for Cathepsin S with an IC₅₀ of 17 nM. BI-1915 can be used in research of autoimmune diseases^[1].

All Cathepsin Isoforms :

Chemical Information

CAS No. 752237-67-5
Molecular Weight 407.55
Formula C₂₁H₃₇N₅O₃
SMILES

O=C(N1CCOCC1)N[C@@H](CCC(C)(C)CC)C(NC2(CCN(CC2)C)C#N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Moss N, et al., Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7189-93. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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BI-1915

All Cathepsin Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BI-1915 Related Classifications

HY-172203 Related Classifications